Carlomagno, C.; Banfi, P. I.; Gualerzi, A.; Picciolini, S.; Volpato, E.; Meloni, M.; Lax, A.; Colombo, E.; Ticozzi, N.; Verde, F.; Silani, V.; Bedoni, M. published the artcile< Human salivary Raman fingerprint as biomarker for the diagnosis of Amyotrophic Lateral Sclerosis>, Application of C6H12O6, the main research area is human amyotrophic lateral sclerosis saliva Raman fingerprint biomarker diagnosis.
Abstract: Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease leading to progressive and irreversible muscle atrophy. The diagnosis of ALS is time-consuming and complex, with the clin. and neurophysiol. evaluation accompanied by monitoring of progression and a long procedure for the discrimination of similar neurodegenerative diseases. The delayed diagnosis strongly slows the potential development of adequate therapies and the time frame for a prompt intervention. The discovery of new biomarkers could improve the disease diagnosis, as well as the therapeutic and rehabilitative effectiveness and monitoring of the pathol. progression. In this work saliva collected from 19 patients with ALS, 10 affected by Parkinson’s disease, 10 affected by Alzheimer’s disease and 10 healthy subjects, was analyzed using Raman spectroscopy, optimizing the parameters for detailed and reproducible spectra. The statistical multivariate anal. of the data revealed a significant difference between the groups, allowing the discrimination of the disease onset. Correlation of Raman data revealed a direct relationship with paraclin. scores, identifying multifactorial biochem. modifications related to the pathol. The proposed approach showed a promising accuracy in ALS onset discrimination, using a fast and sensitive procedure that can make more efficient the diagnostic procedure and the monitoring of therapeutic and rehabilitative processes in ALS.
Scientific Reports published new progress about Alzheimer disease. 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Application of C6H12O6.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts