《Hydrotrifluoromethylthiolation of Unactivated Alkenes and Alkynes with Trifluoromethanesulfonic Anhydride through Deoxygenative Reduction and Photoredox Radical Processes》 was written by Ouyang, Yao; Xu, Xiu-Hua; Qing, Feng-Ling. Related Products of 821-41-0This research focused onunactivated alkene alkyne trifluoromethanesulfonic anhydride hydrotrifluoromethylthiolation deoxygenative reduction photoredox; deoxygenation; hydrotrifluoromethylthiolation; photoredox catalysis; radical reactions; trifluoromethanesulfonic anhydrides. The article conveys some information:
An ongoing challenge in trifluoromethylthiolation reactions is the use of less expensive and easily available trifluoromethylthio sources. Herein, we disclose an unprecedented usage of trifluoromethanesulfonic anhydride (Tf2O) as a radical trifluoromethylthiolating reagent. Hydrotrifluoromethylthiolation of unactivated alkenes and alkynes with Tf2O in the presence of PMePh2 and H2O under visible-light photoredox catalysis gave the addition products. The trifluoromethylthio radical (.SCF3) was first formed from Tf2O through a photoredox radical processes and deoxygenative reduction of PMePh2, and H2O serves as the H-atom donor for the hydrotrifluoromethylthiolation reaction. This reaction provides a new strategy for radical trifluoromethylthiolation. The results came from multiple reactions, including the reaction of 5-Hexen-1-ol(cas: 821-41-0Related Products of 821-41-0)
5-Hexen-1-ol(cas: 821-41-0) is used in cyclization to a tetrahydropyran by phenylselenoetherification. It is also used as a building block in synthetic chemistry.Related Products of 821-41-0
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