Yuan, Shuai; Xu, Chang-Yuan; Xia, Jie; Feng, Yan-Ni; Zhang, Xi-Feng; Yan, You-Yu published the artcile< Extraction of polysaccharides from Codonopsis pilosula by fermentation with response surface methodology>, Electric Literature of 3458-28-4, the main research area is Codonopsis polysaccharide antioxidant response surface methodol; antioxidation; codonopsis; polysaccharide; response surface method.
Codonopsis pilosula is a kind of traditional Chinese medicine used to treat weak spleens, stomach problems, anemia, and fatigue. Polysaccharide is one of main components of Codonopsis pilosula. In this study, response surface methodol. (RSM) was used to optimize the extraction parameters of Codonopsis pilosula polysaccharides (CPP) by fermentation The exaction temperature (°C), yeast liquid volume (2 mg/mL, ml), and time (h) were employed effects. Results indicated that the best extraction conditions were the following: extraction temperature 24.75°C, yeast liquid volume 2.96 mL (5.92 mg), and a fermentation time of 21.03 h. After purification with DE52 and Sephadex G-100, the mol. structure was determined by UV-visible (UV) spectroscopy, Fourier transform IR (FTIR) spectroscopy, and NMR (NMR) (1H and 13C). The monosaccharide composition of CPP1 was determined to be mannose (1.76%), glucose (97.38%), and arabinose (0.76%). CPP1 exhibited high antioxidant activities in scavenging ABTS radicals, ferreous ions, and superoxide ion radicals. Thus, CPP1 could be used as an antioxidant or functional food.
Food Science & Nutrition (Hoboken, NJ, United States) published new progress about Antioxidants. 3458-28-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Electric Literature of 3458-28-4.
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