Deeprose, Mark J.; Lowe, Martin; Noble, Adam; Booker-Milburn, Kevin I.; Aggarwal, Varinder K. published the artcile< Sequential Photocatalytic Reactions for the Diastereoselective Synthesis of Cyclobutane Scaffolds>, HPLC of Formula: 627-27-0, the main research area is cyclobutane preparation regioselective diastereoselective photochem; chlorocyclobutane alkene dechlorinative functionalization photoredox catalyst; chloromaleimide alkyne photocycloaddition hydrogenation.
The synthesis of densely functionalized cyclobutanes containing all-carbon quaternary stereocenters in high regio- and diastereoselectivity remains synthetically challenging. Herein, author show that this can be achieved by using a sequential photocatalysis strategy, wherein 3-chloromaleimides undergo triplet sensitized [2 + 2] photocycloadditions with alkynes or alkenes followed by photoredox-catalyzed dechlorinative C-C bond forming reactions to install quaternary stereocenters. This allows the rapid assembly of structurally complex and sterically congested 3-azabicyclo[3.2.0]heptane scaffolds from readily available starting materials.
Organic Letters published new progress about [2+2] Photocycloaddition reaction. 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, HPLC of Formula: 627-27-0.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts