Donthireddy, S. N. R.; Mathoor Illam, Praseetha; Rit, Arnab published the artcile< Ruthenium(II) Complexes of Heteroditopic N-Heterocyclic Carbene Ligands: Efficient Catalysts for C-N Bond Formation via a Hydrogen-Borrowing Strategy under Solvent-Free Conditions>, Electric Literature of 5344-90-1, the main research area is ruthenium imidazolylidene triazolylidene complex preparation crystal structure benzylation catalyst; crystal structure ruthenium imidazolylidene triazolylidene complex; mol structure ruthenium imidazolylidene triazolylidene complex; benzyl alc coupling reaction benzylation aniline derivative carbeneruthenium catalyst; quinoline derivative preparation.
Both imidazol-2-ylidene (ImNHC) and 1,2,3-triazol-5-ylidene (tzNHC) have evolved to be elite groups of N-heterocyclic carbene (NHC) ligands for homogeneous catalysis. To develop efficient Ru(II)-based catalysts incorporating these ligands for C-N bond-forming reactions via H-borrowing methodol., the authors used chelating ligands integrated with ImNHC and mesoionic tzNHC donors connected via a CH2 spacer with a diverse triazole backbone. The synthesized Ru(II) complexes 3 are highly efficient for C-N bond formation across a wide range of primary amine and alc. substrates under solvent-free conditions, and among all of the complexes studied here, catalyst 3a with a mesityl substituent displayed maximum activity. Catalyst 3a is also effective for the selective mono-N-methylation of various anilines using MeOH as a coupling partner, known to be relatively more difficult than other alcs. Also, complex 3a also delivers various substituted quinolines successfully via the reaction of 2-aminobenzyl alc. with several secondary alcs. Importantly, catalyst 3a exhibited the highest activity among the reported Ru(II) complexes for both the N-benzylation of aniline [achieving a turnover number (TON) of 50000] and the realization of quinoline 8a by reacting 2-aminobenzyl alc. with 2-phenylethanol (attaining a TON of 30000). The significance of electronic tuning in the Ru(II) complexes of chelating ligands featuring a combination of ImNHC and tzNHC donors with various triazole backbones is demonstrated by applying them in diverse C-N bond-forming reactions via a H-borrowing strategy. Notably, the Ru(II) complex 3a having an N-mesityl substituent displayed the highest activity among known Ru(II) complexes for both the N-benzylation of aniline [a turnover number (TON) of 50000] and the synthesis of quinoline via the reaction of 2-aminobenzyl alc. with 2-phenylethanol (a TON of 30000).
Inorganic Chemistry published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Electric Literature of 5344-90-1.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts