Related Products of 3597-91-9 ,Some common heterocyclic compound, 3597-91-9, molecular formula is C13H12O, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
Anoven dried 100 mL round bottom was charged with 2.00 g (10.85 mmol) of biphenyl-4-yl-methanol, 30 mlof chloroform, 10.5g of anhydrous magnesiumsulfate and a magnetic stir bar.The solution was then allowed to stir until the solution was homogenous, 4.5 g of pyridinium chlorochromate was then added and the vessel was sealed and allowed to react for 3 hours. Reaction progress was checked by TLC andonce the reaction was complete excess solvent was removed via rotovap. Thes olution was then purified via a silica column. The purification yielded a yellow oil that was thenre-crystallized into a white crystalline solid with hexane and dichloromethane.(1.90 g, 10.43 mmol, 96%)
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 3597-91-9, [1,1′-Biphenyl]-4-ylmethanol, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Steiger, Scott A.; Li, Chun; Campana, Charles F.; Natale, Nicholas R.; Tetrahedron Letters; vol. 57; 3; (2016); p. 423 – 425;,
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