In 2022,Mouhsine, Bouchaib; Karim, Abdallah; Dumont, Clement; Saint Pol, Anthony; Suisse, Isabelle; Sauthier, Mathieu published an article in European Journal of Organic Chemistry. The title of the article was 《The Selective Nickel-Catalyzed N-Allylation of C3-Unprotected Indoles under Mild and Clean Conditions》.HPLC of Formula: 7748-36-9 The author mentioned the following in the article:
A simple salt free and selective N-allylation of indoles with allylic alcs. was developed. The protocol uses a catalytic amount of a nickel complex generated in situ from Ni(cod)2 and dppf as diphosphine. The use of DMSO as the reaction solvent was crucial to control the regioselectivity of the reaction with the exclusive formation of the N-allyl product among up to three possible products. The experimental part of the paper was very detailed, including the reaction process of Oxetan-3-ol(cas: 7748-36-9HPLC of Formula: 7748-36-9)
Oxetan-3-ol(cas: 7748-36-9) is used as a reagent in the synthesis of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. It is also used as a reagent in the synthesis of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors.HPLC of Formula: 7748-36-9
Referemce:
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Alcohols – Chemistry LibreTexts