Synthetic Route of C3H9NO2In 2019 ,《Synthesis of Porphyrinoids, BODIPYs, and (Dipyrrinato)ruthenium(II) Complexes from Prefunctionalized Dipyrromethanes》 appeared in European Journal of Organic Chemistry. The author of the article were Hohlfeld, Benjamin F.; Flanagan, Keith J.; Kulak, Nora; Senge, Mathias O.; Christmann, Mathias; Wiehe, Arno. The article conveys some information:
The introduction of functional groups into the meso-position of dipyrromethanes, boron-dipyrromethenes (BODIPYs) and porphyrinoids, is of fundamental importance in designing such dye systems for material sciences or photomedicine. One route that proved to be particularly useful in this respect is the nucleophilic aromatic substitution (SNAr) on porphyrinoids and their precursors carrying electron-withdrawing substituents. To further expand this methodol., the potential of the 4-fluoro-3-nitrophenyl and the 3,4,5-trifluorophenyl moieties for the synthesis of functionalized dipyrromethanes, BODIPYs, and porphyrinoids was evaluated. The 3,4,5-trifluorophenyl moiety proved not to be applicable in the SNAr with nucleophiles. The introduction of the 4-fluoro-3-nitrophenyl group, however, allowed fast and efficient SNAr with various amine nucleophiles. The synthesized 4-amino-3-nitrophenyl-substituted dipyrromethanes were successfully applied in the synthesis BODIPYs and were tested in the synthesis of “”trans””-A2B2 porphyrins and A2B corroles. Furthermore, the dipyrromethanes – after oxidation to the dipyrromethenes – are suitable ligands for metal ions giving access to functionalized ruthenium(II) metal complexes.2-Aminopropane-1,3-diol(cas: 534-03-2Synthetic Route of C3H9NO2) was used in this study.
2-Aminopropane-1,3-diol(cas: 534-03-2) belongs to anime. Aniline, ethanolamines, and several other amines are major industrial commodities used in making rubber, dyes, pharmaceuticals, and synthetic resins and fibres and for a host of other applications. Most of the numerous methods for the preparation of amines may be broadly divided into two groups: (1) chemical reduction (replacement of oxygen with hydrogen atoms in the molecule) of members of several other classes of organic nitrogen compounds and (2) reactions of ammonia or amines with organic compounds.Synthetic Route of C3H9NO2
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