Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 4541-15-5, name is 5-(Benzyloxy)pentan-1-ol. This compound has unique chemical properties. The synthetic route is as follows. name: 5-(Benzyloxy)pentan-1-ol
To a solution of triphenylphosphine (6.8 g, 25.7 mmol) in dichloromethane (100 mL) at 0 C was added bromine (1.3 mL, 25.7 mmol) and the mixture stirred for 30 minutes. A solution of the alcohol 33 (5.0 g, 25.7 mmol) in dichloromethane (20 mL) and pyridine (2.1 mL, 25.7 mmol) were added and the mixture was warmed to room temperature and stirred for 4 hours. The volatiles were removed and the residue suspended in water (200 mL), extracted with diethyl ether (3 x 100 mL) and dried over anhydrous magnesium sulfate. The ethereal extracts were concentrated (to ~100 mL) and hexane (100 mL) was added. The resulting precipitate was removed by filtration and the filtrate was aged at -30 C for 24 hours. The large crystals of triphenylphosphine oxide were removed by filtration and the filtrate concentrated to obtain the title compound 34 (5.8 g, 88%) as a colourless oil, the spectroscopic data of which corresponded to previously described. Rf: 0.34 (1:19 ethyl acetate, hexane).
If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 4541-15-5, 5-(Benzyloxy)pentan-1-ol.
Reference:
Article; Moir, Michael; Lane, Samuel; Lai, Felcia; Connor, Mark; Hibbs, David E.; Kassiou, Michael; European Journal of Medicinal Chemistry; vol. 180; (2019); p. 291 – 309;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts