Kiskova, Terezia; Kubatka, Peter; Busselberg, Dietrich; Kassayova, Monika published the artcile< The plant-derived compound resveratrol in brain cancer: a review>, Related Products of 501-36-0 , the main research area is review brain cancer resveratrol; brain cancer; drug resistance; glioblastoma; resveratrol.
A review. Despite intensive research, malignant brain tumors are among the most difficult to treat due to high resistance to conventional therapeutic approaches. High-grade malignant gliomas, including glioblastoma and anaplastic astrocytoma, are among the most devastating and rapidly growing cancers. Despite the ability of standard treatment agents to achieve therapeutic concentrations in the brain, malignant gliomas are often resistant to alkylating agents. Resveratrol is a plant polyphenol occurring in nuts, berries, grapes, and red wine. Resveratrol crosses the blood-brain barrier and may influence the central nervous system. Moreover, it influences the enzyme isocitrate dehydrogenase and, more importantly, the resistance to standard treatment via various mechanisms, such as O6-methylguanine methyltransferase. This review summarizes the anticancer effects of resveratrol in various types of brain cancer. Several in vitro and in vivo studies have presented promising results; however, further clin. research is necessary to prove the therapeutic efficacy of resveratrol in brain cancer treatment.
Biomolecules published new progress about Astrocytoma. 501-36-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C14H12O3, Related Products of 501-36-0 .
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