Chaudhari, Anand Kumar’s team published research in Natural Product Research in 2020 | 78-70-6

Natural Product Research published new progress about Aspergillus flavus. 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, Recommanded Product: 3,7-Dimethylocta-1,6-dien-3-ol.

Chaudhari, Anand Kumar; Singh, Vipin Kumar; Dwivedy, Abhishek Kumar; Das, Somenath; Upadhyay, Neha; Singh, Akanksha; Dkhar, Mumtaz S.; Kayang, Highland; Prakash, Bhanu; Dubey, Nawal Kishore published the artcile< Chemically characterized Pimenta dioica (L.) Merr. essential oil as a novel plant based antimicrobial against fungal and aflatoxin B1 contamination of stored maize and its possible mode of action>, Recommanded Product: 3,7-Dimethylocta-1,6-dien-3-ol, the main research area is Pimenta essential oil antimicrobial agent maize aflatoxin B1 contamination; Pimenta dioica essential oil; aflatoxin B1; ergosterol; lipid peroxidation; methylglyoxal; α-Terpineol.

The chem. characterization of P. dioica essential oil (PDEO) revealed the presence of 50 components, among which α-terpineol (30.31%) was the major component followed by β-linalool (6.75%) and γ-terpinene (4.64%). The oil completely inhibited the growth of aflatoxin B1-secreting strain Aspergillus flavus LHP-VS-8, and aflatoxin B1 production at 2.5 and 1.5μL/mL, resp. The oil caused dose-dependent reduction of methylglyoxal (an AFB1 inducer), enhanced leakage of Ca2+, Mg2+ and K+ ions, and significantly reduced the ergosterol content of the fungal plasma membrane. During in situ experiments, PDEO exhibited complete protection of fumigated maize cob slices from fungal infestation without affecting seed germination. The chem. characterized PDEO is recommended as a plant based preservative and shelf life enhancer of food commodities by preventing fungal growth, AFB1 production and lipid peroxidation This is the 1st report on PDEO as inhibitor of AFB1 secretion, and methylglyoxal biosynthesis.

Natural Product Research published new progress about Aspergillus flavus. 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, Recommanded Product: 3,7-Dimethylocta-1,6-dien-3-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts