Kulyk, Dmytro S.; Wan, Qiongqiong; Sahraeian, Taghi; Badu-Tawiah, Abraham K. published the artcile< Dehydration of gas-phase benzyl amine alcohols studied at atmospheric pressure>, Recommanded Product: (2-Aminophenyl)methanol, the main research area is benzyl alc dehydration mechanism mass spectrum.
Gas-phase ion chem. is a useful approach for the investigation of phys. organic chem. and the study of reactivity, structure, and thermochem. properties of ionic and neutral organic substrates. Herein, one-step dehydration of gas-phase benzyl amine alcs. to give benzazetidines was discovered without the use of catalysts. Mechanistic investigations of the gas-phase dehydration reactions were explored to study the possible influence of charged microdroplet acceleration during electrospray ionization (ESI) and collisions occurring during ion transfer through the atm. pressure interface (API) of the mass spectrometer. The product ion distribution was observed to be less sensitive to droplet effects (spray distance and voltage), and temperature of transfer capillary in the API. However, the product ion distribution exhibit high sensitivity to different S-lens radio frequency (RF) voltage of the API, providing evidence that the dehydration reaction is driven by collisions during ion transfer in the API. With this insight, we developed atm. pressure thermal dissociation platform that allowed thermal-induced collisions outside of the mass spectrometer when the benzyl amine alcs. are carried through a heated coiled tube. Up to 98% dissociation efficiency was achieved with the coiled tube heated to a temperature of 200°C, yielding only the desired benzazetidine product. By performing the atm. pressure thermal dissociation experiment outside of the mass spectrometer, we believe it will be straightforward to collect the dehydration product.
International Journal of Mass Spectrometry published new progress about Atmospheric chemistry. 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Recommanded Product: (2-Aminophenyl)methanol.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts