Talavera-Aleman, Armando; Marrot, Jerome; Dagousset, Guillaume; Thomassigny, Christine published the artcile< Synthesis of Nitrogen- and Oxygen-Containing Heterocycles by Prins Cyclization in Continuous Flow>, Product Details of C4H8O, the main research area is tetrahydropyridine preparation; amine aldehyde aza silyl Prins cyclization; tetrahydropyran preparation; aldehyde butenol oxa Prins cyclization.
Aza-silyl-Prins and oxa-Prins cyclization reactions in continuous-flow chem. were described for the synthesis of the corresponding tetrahydropyridines I [R = Ph, Bn; R1 = Bu, CH(CH3)CH2CH2CH3, Bn, CH2CH2C6H5] and pyran derivatives, II [R = heptyl, cyclohexyl, 4-NO2C6H4] resp. In particular, the use of pyridine-carboxaldehydes for aza-silyl-Prins reaction led to either a sym. triarylmethane or two new bicyclic compounds 4-Fluorinated-2-substituted tetrahydropyran derivatives III [stereo = cis, anti] were also obtained in the oxa-Prins cyclization with good selectivity in favor of the anti-isomer.
Synthesis published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Product Details of C4H8O.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts