Yang, Bo; Li, Shi-Jun; Wang, Yongdong; Lan, Yu; Zhu, Shifa published the artcile< Hydrogen radical-shuttle (HRS)-enabled photoredox synthesis of indanones via decarboxylative annulation>, Recommanded Product: (4-Ethynylphenyl)methanol, the main research area is phenylglyoxalic acid acetylene iridium photocatalyst regioselective decarboxylative cyclization; dihydroindenone preparation.
In this work, a HRS-enabled decarboxylative annulation of carbonyl compounds via photoredox catalysis for the synthesis of indanones was developed. This protocol features broad substrate scope, excellent functional group tolerance, internal hydrogen radical transfer, atom- and step-economy. Critical to the success of this process is the introduction of water, acting as both HRS and hydrogen source, which was demonstrated by mechanistic experiments and d. functional theory (DFT) calculations Importantly, this mechanistically distinctive HAT provides a complement to that of typical proton-shuttle-promoted, representing a breakthrough in hydrogen radical transfer, especially in the inherently challenging 1,2- or 1,3-HAT.
Nature Communications published new progress about Alkynes, internal Role: RCT (Reactant), RACT (Reactant or Reagent). 10602-04-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C9H8O, Recommanded Product: (4-Ethynylphenyl)methanol.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts