Suvarna, Vasanti; Gujar, Parul; Murahari, Manikanta; Sharma, Dhvani; Chamariya, Rinkal published an article on January 31 ,2022. The article was titled 《Supramolecular ternary inclusion complexes of Irbesartan with hydroxypropyl-beta-cyclodextrin》, and you may find the article in Journal of Drug Delivery Science and Technology.Computed Properties of C6H12O6 The information in the text is summarized as follows:
Current study investigated the formation of binary and ternary inclusion complexes of Irbesartan (IRB) with Hydroxypropyl-β-Cyclodextrin (HP-βCD) as host and L-Arginine (L-Arg) as ternary agent. Inclusion complexes were characterized using solubility, invitro release, DSC and XRD studies. Host-guest interactions were explored by FTIR, 1H NMR and mol. docking studies. Significant enhancement in stability constant and complexation efficiency of HP-βCD was observed in ternary complexes due to the presence of L-Arg. Ternary complexes exhibited greater solubility and dissolution of IRB than binary complexes. Thus, ternary complexation of IRB could offer an innovative strategy for improvement of solubility and dissolution of IRB. In the part of experimental materials, we found many familiar compounds, such as rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol(cas: 54-17-1Computed Properties of C6H12O6)
rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol(cas: 54-17-1) is the monohydrate form of the alpha isoform of D-glucopyranose, a synthetic simple monosaccharide that is used as an energy source.Computed Properties of C6H12O6
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