Sugimoto, Kenji; Mizuno, Shota; Shirato, Misaki; Tanabe, Kosuke; Matsuya, Yuji published the artcile< De novo approach to izidines via a gold-catalyzed hydroamination-N-acyliminium ion cyclization of acyclic ynamides>, Safety of But-3-en-1-ol, the main research area is acyclic ynamide preparation gold catalyst tandem hydroamination heterocyclization; izidine preparation.
A gold(I)-catalyzed novel domino reaction of acyclic ynamides yielding nitrogen-fused bicyclic skeletons was described. The reaction with 10 mol% JohnPhosAuNTf2 and stoichiometric amount of PhCO2H enables constructions of quinolizidine and indolizidine skeleton having tetrasubstituted carbon center. Especially in the case of quinolizidine synthesis, the quaternary stereogenic center was furnished under highly diastereoselective manner.
Heterocycles published new progress about Diastereoselective synthesis. 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Safety of But-3-en-1-ol.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts