Nandi, Poulomi; Goel, Komal; Sreenivasulu, Chinnabattigalla; Satyanarayana, Gedu published the artcile< Microwave-Assisted Condensation of Benzylic Alcohols and Alkynes Promoted by Zinc Halides: Concise Access to Alkenyl Halides>, Synthetic Route of 76-84-6, the main research area is benzylic alc terminal alkyne zinc halide condensation microwave green; alkenyl halide indene ketone preparation regioselective.
A simple Lewis acid-mediated route for the synthesis of alkenyl halides under microwave-assisted conditions is described. The reaction proceeds through condensation of secondary alcs. with terminal acetylenes and regioselective hydrohalogenation across the triple bond in the presence of simple and com. available zinc halides. Unlike earlier reports, the methodol. is successfully exemplified with three halide sources. As a result, a diverse range of alkenyl halide products have been obtained. Further, indenes were obtained as the end products when tertiary alcs. and arylacetylenes were used, wherein the Thorpe-Ingold and electronic effects, would be dominant. Furthermore, when an electron-rich arylacetylene was employed, the reaction yielded carbonyl products.
European Journal of Organic Chemistry published new progress about Alkyl aryl ketones Role: SPN (Synthetic Preparation), PREP (Preparation). 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Synthetic Route of 76-84-6.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts