In the chemical reaction process,reaction time,type of solvent,can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product.An updated downstream synthesis route of 2807-30-9 as follows., 2807-30-9
General procedure: Method A To a solution of compound 3 (150 mg, o.27 mmol), alcohol (0.81 mmol), and EDCI (576 mg, 3.0 mmol) in CH2Cl2 (30 mL) was added DMAP (122 mg, 1.0 mmol), and the mixture was stirred at room temperature for 12 h. Ethyl acetate (60 mL) was added, and the organic phase was washed three times with water, once with brine, dried, and finally concentrated. There is no need to further purify the residue.
The chemical industry reduces the impact on the environment during synthesis 2807-30-9, I believe this compound will play a more active role in future production and life.
Reference:
Article; Liu, Shan Xiang; Jin, Hui Zi; Shan, Lei; Zeng, Hua Wu; Chen, Bing Yang; Sun, Qing Yan; Zhang, Wei Dong; Bioorganic and Medicinal Chemistry Letters; vol. 23; 7; (2013); p. 2207 – 2211;,
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