Boekman, C. Fredrik; Zettersten, Camilla; Sjoeberg, Per J. R.; Nyholm, Leif published the artcile< A setup for the coupling of a thin-layer electrochemical flow cell to electrospray mass spectrometry>, Name: Sodium 5,5′-(diazene-1,2-diyl)bis(2-hydroxybenzoate), the main research area is thin layer electrochem flow cell electrospray mass spectrometer coupling; Olsalazine hexanethiol electrochem oxidation electrospray mass spectrometry.
A novel setup for the coupling of a com. available thin-layer cell to electrospray mass spectrometry (ESI-MS) which allows the electrochem. reactions at the counter electrode to be straightforwardly separated from the flow into the mass spectrometer was developed. In this way, interferences from reaction products formed at the counter electrode can be minimized. This reduces the risk of changes in the mass spectra as a result of electrochem. reactions in the solution The described setup also enables the working electrode to be positioned close to the electrospray (ESI) emitter without the need for a grounding point or a long transfer line between the electrochem. cell and the electrospray emitter. By decoupling the electrochem. reactions in the flow cell and those in the electrospray emitter, improved facilities for studies of electrochem. reactions were obtained through a better control of the potential of the working electrode. The setup was used to study the oxidation of a drug (Olsalazine), which previously was found to involve chem. follow-up reactions. Also uncharged thiols can be detected in ESI-MS after spontaneous adsorption on a gold working electrode, followed by oxidative desorption to yield sulfinates or sulfonates. This adsorption and potential-controlled desorption was used for the preconcentration of micromolar concentrations of 1-hexanethiol as well as for desalting of solutions containing micromolar concentrations of thiols. The present online coupling of an electrochem. cell to ESI-MS provides promising possibilities for sample preconcentration, matrix exchange (including desalting), and ionization of neutral compounds, such as thiols.
Analytical Chemistry published new progress about Electrochemical oxidation. 6054-98-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C14H8N2Na2O6, Name: Sodium 5,5′-(diazene-1,2-diyl)bis(2-hydroxybenzoate).
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts