Adding a certain compound to certain chemical reactions, such as: 2919-23-5, Cyclobutanol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Formula: C4H8O, blongs to alcohols-buliding-blocks compound. Formula: C4H8O
A quartz glass tube charged with 50 g of catalyst (H1044, composition approx. 27 g of copper oxide, approx. 4 g of chromium oxide, approx. 5 g of barium oxide, on SiO2) and bounded at both ends with Raschig rings was installed in a commercial, electrically heated laboratory tubular furnace and the temperature in the catalyst zone was set to 200 C. 30 g of crude cyclobutanol product (purity approx. 73%, 0.3 mol) were evaporated using a preevaporator and then passed over the catalyst (LHSV=0.18/h). After leaving the catalyst zone, the reaction mixture was cooled using a condenser and collected in a cold trap. 27 g of reaction effluent were obtained, having a composition of 59% of cyclobutanone and 19% of cyclobutanol (conversion: 77%, selectivity: 96%). Example 7 Gas Phase Dehydrogenation [0043] In the experimental apparatus described in Example 6 (same catalyst), 256 g of crude cyclobutanol (purity approx. 74%) were converted at 250 C. (LHSV=0.33/h). 243 g of reaction effluent were obtained having an average composition of 63% of cyclobutanone and 12% of cyclobutanol (conversion: 84%, selectivity >98%). Distillation of the product mixture through a 1 m Multifil column provided 102 g of cyclobutanone in a purity of >99% (b.p.: 97-99 C., distillation yield: 67%). Example 8 Gas Phase Dehydrogenation [0044] The quartz glass tube was filled with 50 g of catalyst (H1044, calcined at 700 C.) and was stored in the laboratory tubular furnace as in Example 7. Likewise as described, 135 g (1.3 mol) of crude cyclobutanol (purity 71%) were passed over the catalyst at 250 C. (LHSV=0.33/h). 127 g of reaction effluent were obtained having an average composition of 58% of cyclobutanone and 2.5% of cyclobutanol (conversion: 97%, selectivity: 82%). Example 9 Gas Phase Dehydrogenation [0045] The quartz glass tube was filled with 50 g of catalyst (H1044, calcined at 650 C.) and stored in the laboratory tubular furnace as described in Example 7. 776 g of crude cyclobutanol (purity: 71%) were then passed in gaseous form over the catalyst at 250 C. (LHSV=0.33/h). 719 g of reaction effluent were obtained having an average composition of 67% of cyclobutanone and 5% of cyclobutanol (conversion: 94%, selectivity: 97%). Distillation of the product mixture through a 1 m Multifil column resulted in 380 g of cyclobutanone (purity >95%, distillation yield 81%). Example 10 Gas Phase Dehydrogenation [0046] The quartz glass tube was filled with 50 g of catalyst (H1044, calcined at 650 C.) and stored in the laboratory tubular furnace as described in Example 7. 876 g of crude cyclobutanol (purity: 75%) were then passed in gaseous form over the catalyst at 250 C. (LHSV=1.5 h-1). 832 g of reaction effluent were obtained having an average composition of 67% of cyclobutanone and 8% of cyclobutanol (conversion: 90%, selectivity: 97%). Distillation of the product mixture through a 1 m Multifil column resulted in 516 g of cyclobutanone (purity >95%, distillation yield 80%)
The synthetic route of 2919-23-5 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Degussa AG; US2004/254401; (2004); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts