Determination of codeine in terpin hydrate and codeine elixir was written by Blake, Martin I.;Carlstedt, Bruce. And the article was included in Journal of Pharmaceutical Sciences in 1966.Computed Properties of C10H22O3 This article mentions the following:
Ion-exchange chromatography and nonaqueous titrimetry and applied to the analysis of codeine in terpin hydrate and codeine elixir. The method is simple and accurate. In the experiment, the researchers used many compounds, for example, rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6Computed Properties of C10H22O3).
rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Computed Properties of C10H22O3
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts