Month: February 2023

Well-Defined Ni-SNS Complex Catalyzed Borrowing Hydrogenative α-Alkylation of Ketones and Dehydrogenative Synthesis of Quinolines was written by Sharma, Rahul;Mondal, Avijit;Samanta, Arup;Biswas, Nandita;Das, Babulal;Srimani, Dipankar. And the article was included in Advanced Synthesis & Catalysis in 2022.Formula: C7H7ClO This article mentions the following:

Here presented a synthesis of non-phosphine, easily accessible and bench stable SNS-Ni complexes. The Ni-catalyst was successfully applied for the C-alkylation of ketone enolates to α-alkylated ketones. Primary alc. with different functional groups and various heteroaromatic alcs. were well tolerated. The present catalyst system was efficiently applied to gram scale synthesis and also the green chem. metrics of the reaction were calculated The present protocol was also extended successfully for the synthesis of biol. important quinoline moieties. Finally, various control experiments and deuterium labeled experiments suggested that the reaction proceeds via borrowing hydrogen pathway. In the experiment, the researchers used many compounds, for example, (4-Chlorophenyl)methanol (cas: 873-76-7Formula: C7H7ClO).

(4-Chlorophenyl)methanol (cas: 873-76-7) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Formula: C7H7ClO

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Evaluation of the role of graphene-based Cu(I) catalysts in borylation reactions was written by Franco, Mario;Sainz, Raquel;Lamsabhi, Al Mokhtar;Diaz, Cristina;Tortosa, Mariola;Cid, M. Belen. And the article was included in Catalysis Science & Technology in 2021.HPLC of Formula: 68716-49-4 This article mentions the following:

Graphene-supported Cu(I) species were prepared by reduction of CuCl₂ adsorbed on graphene oxide surface and examined for catalytic performance in alkyl halide borylation with B₂pin₂, giving alkylboronates. Carbon-supported catalysts have been considered as macromol. ligands which modulate the activity of the metallic catalytic center. Understanding the properties and the factors that control the interactions between the metal and support allows a fine tuning of the catalyzed processes. Although huge effort has been devoted to comprehending binding energies and charge transfer for single atom noble metals, the interaction of graphenic surfaces with cheap and versatile Cu(I) salts has been scarcely studied. A methodical exptl. and theor. anal. of different carbon-based Cu(I) materials in the context of the development of an efficient, general, scalable, and sustainable borylation reaction of aliphatic and aromatic halides has been performed. We have also examined the effect of microwave (MW) radiation in the preparation of these type of materials using sustainable graphite nanoplatelets (GNP) as a support. A detailed anal. of all the possible species in solution revealed that the catalysis is mainly due to an interesting synergetic Cu₂O/graphene performance, which has been corroborated by an extensive theor. study. We demonstrated through DFT calculations at a high level of theory that graphene enhances the reactivity of the metal in Cu₂O against the halide derivative favoring a radical departure from the halogen. Moreover, this material is able to stabilize radical intermediates providing unexpected pathways not observed using homogeneous Cu(I) catalyzed reactions. Finally, we proved that other common carbon-based supports like carbon black, graphene oxide and reduced graphene oxide provided poorer results in the borylation process. In the experiment, the researchers used many compounds, for example, 2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 68716-49-4HPLC of Formula: 68716-49-4).

2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 68716-49-4) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.HPLC of Formula: 68716-49-4

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

New (-)-menthol-based blue phase liquid crystals with different polar substituents in the terminal group: synthesis, mesophase behaviors, and DFT calculations was written by Han, Zhi-Yuan;Kun, Shi-Qian;Kang, Jing-Tian;Jia, Ying-Gang. And the article was included in Journal of Molecular Structure in 2022.SDS of cas: 2216-51-5 This article mentions the following:

Eight novel Schiff base ester chiral liquid crystals I (R = 4-XC₆H₄; X = H, Me, F, NO₂, MeO, CN, CF₃, CF₃O), containing (-)-menthol at one end and a different polar substituent at the other end, were successfully synthesized and analyzed for their mesophase formation and stability. The combination differential scanning calorimeter (DSC), polarizing optical microscopy (POM) and X-ray diffraction (XRD) measurements were carried out to systematically study the mesomorphic properties. The photophys. properties was studied by UV-vis spectroscopy. All the prepared chiral liquid crystals, except for the compound I (R = Ph), are mesomorphic exhibiting N* and/or S_A* mesophase. The results revealed that the mesomorphic behavior and the clearing point of mesophase (T_c) correlate well with polarizability anisotropy (Δα). In the experiment, the researchers used many compounds, for example, (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5SDS of cas: 2216-51-5).

(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.SDS of cas: 2216-51-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Iron-Catalyzed Borrowing Hydrogen β-C(sp³)-Methylation of Alcohols was written by Polidano, Kurt;Williams, Jonathan M. J.;Morrill, Louis C.. And the article was included in ACS Catalysis in 2019.Product Details of 94022-96-5 This article mentions the following:

Herein we report the iron-catalyzed β-C(sp³)-methylation of primary alcs. using methanol as a C1 building block. This borrowing hydrogen approach employs a well-defined bench-stable (cyclopentadienone)iron(0) carbonyl complex as precatalyst (5 mol %) and enables a diverse selection of substituted 2-arylethanols to undergo β-C(sp³)-methylation in good isolated yields (24 examples, 65% average yield). In the experiment, the researchers used many compounds, for example, 2-(Trifluoromethyl)phenethyl alcohol (cas: 94022-96-5Product Details of 94022-96-5).

2-(Trifluoromethyl)phenethyl alcohol (cas: 94022-96-5) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Product Details of 94022-96-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Enantioselective reduction of ortho-substituted acetophenones by bacterial strains isolated from medium enriched with biphenyl or diesel fuel was written by Andrade, Leandro H.;Comasseto, Joao V.;Rodrigues, Debora F.;Pellizari, Vivian H.;Porto, Andre L. M.. And the article was included in Journal of Molecular Catalysis B: Enzymatic in 2005.Recommanded Product: (S)-1-(2-Fluorophenyl)ethanol This article mentions the following:

Application of 21 new bacterial strains from natural environments (coastal plain of Santos and Atlantic Rain Forest, Sao Paulo, Brazil) in the asym. reduction of acetophenone derivatives is described. The bioreduction was carried out with whole bacterial cells leading to (S)-chiral alcs. in up to ≥99% e.e. The (S)-(-)-1-(2-bromophenyl)ethanol was employed in the preparation of chiral tellurium derivatives In the experiment, the researchers used many compounds, for example, (S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4Recommanded Product: (S)-1-(2-Fluorophenyl)ethanol).

(S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Recommanded Product: (S)-1-(2-Fluorophenyl)ethanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Synthesis of an oil absorbent polymer particle with core-shell structure was written by Yang, Fajie;Li, Guoping;Zhang, Zhiheng;Cheng, Lei;Liu, Weili;Liu, Shaozhu. And the article was included in Youqitian Huanjing Baohu in 2014.Quality Control of Diethyleneglycoldiacrylate This article mentions the following:

The core structure of absorbent polymer particle was synthesized by suspension polymerization using Bu acrylate and n-laurylacrylate as monomers, diethylene glycol diacrylate as crosslinking agent, 2,2′-Azobis (2-methylpropionitrile) as initiator. Then, the shell structure was synthesized at the outer surface of the polymer particle using divinylbenzene and phenylethylene as monomers. The effects of the ratio of monomer amounts of core to that of shell, the category and amount of crosslinking agent and initiation temperature on the absorbent ability were studied. The oil absorbent polymer particle with core-shell structure was synthesized with the absorption capacity of 29 g/g. Saturation absorption time of the absorbent polymer particle with core-shell was 3 min, and it was markedly faster than that without core-shell structure. In the experiment, the researchers used many compounds, for example, Diethyleneglycoldiacrylate (cas: 4074-88-8Quality Control of Diethyleneglycoldiacrylate).

Diethyleneglycoldiacrylate (cas: 4074-88-8) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Quality Control of Diethyleneglycoldiacrylate

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Formal β-C-H Arylation of Aldehydes and Ketones by Cooperative Nickel and Photoredox Catalysis was written by Liu, Kun;Studer, Armido. And the article was included in Angewandte Chemie, International Edition in 2022.Recommanded Product: 68716-49-4 This article mentions the following:

A method that uses cooperative nickel and photoredox catalysis for the formal β-C-H arylation of aldehydes and ketones via their readily prepared enol ethers e.g., [(2-methylprop-1-en-1-yl)oxy]tris(propan-2-yl)silaneas with (hetero)aryl bromides RBr (R = Ph, 1-benzofuran-5-yl, quinolin-3-yl, etc.) were reported. The method features mild conditions, remarkable scope and wide functional group tolerance. Importantly, the introduced synthetic strategy also allows the β-alkenylation, β-alkynation and β-acylation of aldehydes under similar conditions. Mechanistic studies revealed that this transformation proceeds through a single electron oxidation/Ni-mediated coupling/reductive elimination cascade. In the experiment, the researchers used many compounds, for example, 2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 68716-49-4Recommanded Product: 68716-49-4).

2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 68716-49-4) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Recommanded Product: 68716-49-4

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Crosslinking Polymer Brushes with Ethylene Glycol-Containing Segments: Influence on Physicochemical and Antifouling Properties was written by Dehghani, Ella S.;Spencer, Nicholas D.;Ramakrishna, Shivaprakash N.;Benetti, Edmondo M.. And the article was included in Langmuir in 2016.Electric Literature of C16H26O7 This article mentions the following:

The introduction of different types and concentrations of crosslinks within poly(hydroxyethyl methacrylate) (PHEMA) brushes influences their interfacial, physicochem. properties, ultimately governing their adsorption of proteins. PHEMA brushes and brush-hydrogels were synthesized by surface-initiated, atom-transfer radical polymerization (SI-ATRP) from HEMA, with and without the addition of di(ethylene glycol) dimethacrylate (DEGDMA) or tetra(ethylene glycol) dimethacrylate (TEGDMA) as crosslinkers. Linear (pure PHEMA) brushes show high hydration and low modulus and addnl. provide an efficient barrier against nonspecific protein adsorption. In contrast, brush-hydrogels are stiffer and less hydrated, and the presence of crosslinks affects the entropy-driven, conformational barrier that hinders the surface interaction of biomols. with brushes. This leads to the physisorption of proteins at low concentrations of short crosslinks. At higher contents of DEGDMA or in the presence of longer TEGDMA-based crosslinks, brush-hydrogels recover their antifouling properties due to the increase in interfacial water association by the higher concentration of ethylene glycol (EG) units. In the experiment, the researchers used many compounds, for example, ((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate) (cas: 109-17-1Electric Literature of C16H26O7).

((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate) (cas: 109-17-1) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Electric Literature of C16H26O7

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Sonochemical synthesis and characterization of CuInS₂ nanostructures using new sulfur precursor and their application as photocatalyst for degradation of organic pollutants under simulated sunlight was written by Jafarinejad, Aazam;Bashiri, Hadis;Salavati-Niasari, Masoud. And the article was included in Arabian Journal of Chemistry in 2022.Synthetic Route of C3H8O2 This article mentions the following:

In this research, we investigated the photocatalytic activity of CuInS₂ nanoparticles in visible light during the decomposition of three toxic dyes (Eriochrome Black T, Rhodamine B, and Erythrosine). The CuInS₂ nanostructures were synthesized by a rapid and simple sonochem. method using dithiooxamide as a sulfur reagent and various capping agents, including SDS, CTAB, and PVP, were applied to achieve a pure structure with fine morphol. The flower-like structure was observed through FESEM images, implying different capping agents and fabrication had a considerable influence on the morphol. of samples. The suitable bandgap of CuInS₂ (1.53 eV) was obtained from DRS anal. and resulted in higher photodegradation efficiency. The fabricated CuInS₂ revealed better photodegradation efficiency (74.8%) to the anionic dyes than cationic dye. A possible photodegradation mechanism was suggested based on scavenger tests of active species. In the experiment, the researchers used many compounds, for example, 1,2-Propanediol (cas: 57-55-6Synthetic Route of C3H8O2).

1,2-Propanediol (cas: 57-55-6) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Synthetic Route of C3H8O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Tris(tetrabutylammonium) hexakis(tert-butanethiolato-κS)hepta-μ₃-chlorido-μ₃-sulfidohexamolybdate dihydrate was written by Petrov, Pavel A.;Naumov, Dmitry Yu.;Konchenko, Sergey N.. And the article was included in Acta Crystallographica, Section E: Structure Reports Online in 2012.Quality Control of Sodium 2-methyl-2-propanethiolate This article mentions the following:

The octahedral cluster core of the anion in the structure of the title compound, (C₁₆H₃₆N)₃[Mo₆(C₄H₉S)₆(μ₃-Cl)₇(μ₃-S)]·2H₂O, has 3̅ site symmetry. Two μ₃-Cl atoms fully occupy positions in the cluster core, while the remaining six positions are statistically occupied by Cl and S atoms in a 1:5 ratio. The fully occupied Cl-atom positions are located on sites with 3 symmetry, and the N atom of tetrabutylammonium cation is located on a site with 2 symmetry. The structure contains also two disordered solvent H₂O mols., one of which is located on a 3-fold rotation axis and the other in a general position, both with an occupancy of 0.25. The H₂O mols. are localized in cavities formed by the tetrabutylammonium cations and the tert-butanethiolate groups. The metal clusters are stacked in a cubic close packing arrangement along [001]. Crystallog. data and at. coordinates are given. In the experiment, the researchers used many compounds, for example, Sodium 2-methyl-2-propanethiolate (cas: 29364-29-2Quality Control of Sodium 2-methyl-2-propanethiolate).

Sodium 2-methyl-2-propanethiolate (cas: 29364-29-2) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Quality Control of Sodium 2-methyl-2-propanethiolate

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts