Production of (R)-chiral alcohols by a hydrogen-transfer bioreduction with NADH-dependent Leifsonia alcohol dehydrogenase (LSADH) was written by Inoue, Kousuke;Makino, Yoshihide;Itoh, Nobuya. And the article was included in Tetrahedron: Asymmetry in 2005.COA of Formula: C8H9ClO This article mentions the following:
Alc. dehydrogenase (LSADH) isolated from Leifsonia sp. S749 was used to produce (R)-chiral alcs. The enzyme with a broad substrate range reduced various prochiral ketones and keto esters to yield optically active secondary alcs. with a high enantiomeric excess. LSADH transferred the pro-S hydrogen of NADH to the carbonyl moiety of Ph trifluoromethyl ketone (13) through its re face to give (S)-1-phenyl-2,2,2-trifluoroethanol (40). LSADH was able to efficiently reproduce NADH when 2-propanol was used as a hydrogen donor in the reaction mixture In the experiment, the researchers used many compounds, for example, (R)-1-(3-Chlorophenyl)ethanol (cas: 120121-01-9COA of Formula: C8H9ClO).
(R)-1-(3-Chlorophenyl)ethanol (cas: 120121-01-9) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.COA of Formula: C8H9ClO
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts