An environmentally-friendly one-pot synthesis of 4-sulfonyl benzoic acids was written by Frieman, Bryan A.. And the article was included in Tetrahedron Letters in 2014.SDS of cas: 29364-29-2 This article mentions the following:
This Letter reported an environmentally-friendly one-pot SNAr reaction of thiols to 4-halobenzoic acid Me esters to provide 4-substituted sulfone benzoic acids and picolinic acids after bleach-mediated oxidative workup. These acid intermediates were synthesized on gram scale, are perfect partners for library synthesis, and have good phys. chem. properties useful for drug discovery. In the experiment, the researchers used many compounds, for example, Sodium 2-methyl-2-propanethiolate (cas: 29364-29-2SDS of cas: 29364-29-2).
Sodium 2-methyl-2-propanethiolate (cas: 29364-29-2) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.SDS of cas: 29364-29-2
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts