Localizable and Photoactivatable Fluorophore for Spatiotemporal Two-Photon Bioimaging was written by Zhou, Liyi;Zhang, Xiaobing;Lv, Yifan;Yang, Chao;Lu, Danqing;Wu, Yuan;Chen, Zhuo;Liu, Qiaoling;Tan, Weihong. And the article was included in Analytical Chemistry (Washington, DC, United States) in 2015.Related Products of 60463-12-9 This article mentions the following:
Photoactivatable probe-based fluorescent imaging has become an efficient and attractive technique for spatiotemporal microscopic studies of biol. events. However, almost all previously reported photoactivatable organic probes have been based on hydrosol. precursors, which produced water-soluble active fluorophores able to readily diffuse away from the photocleavage site, thereby dramatically reducing spatial resolution Hydroxyphenylquinazolinone (HPQ), a small organic dye known for its classic luminescence mechanism through excited-state intramol. proton transfer (ESIPT), shows strong light emission in the solid state, but no emission in solution HPQ was employed as a precursor to develop a localizable, photoactivatable two-photon probe (PHPQ) for spatiotemporal bioimaging applications. After photocleavage, PHPQ releases a precipitating HPQ fluorophore which shows both one-photon and two-photon excited yellow-green fluorescence, thereby producing a localizable fluorescence signal that affords high spatial resolution for bioimaging, with >200-fold one-photon and 150-fold two-photon fluorescence enhancement. In the experiment, the researchers used many compounds, for example, 3-(Hydroxymethyl)-4-nitrophenol (cas: 60463-12-9Related Products of 60463-12-9).
3-(Hydroxymethyl)-4-nitrophenol (cas: 60463-12-9) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Related Products of 60463-12-9
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts