Palladium-catalyzed Heck cyclization/carbonylation with formates: synthesis of azaindoline-3-acetates and furoazaindolines was written by Ye, Hao;Wu, Linhui;Zhang, Minrui;Jiang, Guomin;Dai, Hong;Wu, Xin-Xing. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2022.Application In Synthesis of Benzo[d][1,3]dioxol-4-ol This article mentions the following:
Herein a palladium-catalyzed domino cyclization/carbonylation to access ester-functionalized azaindolines, e.g., I applying formates, e.g., phenylformate as a convenient carbonyl source was reported. All four azaindoline isomers were constructed, exhibiting good functional group compatibility. On this basis, modifying the starting tether on the aminopyridine led to furoazaindolines, e.g., II via an intramol. reductive cyclization after the palladium-catalyzed process. In the experiment, the researchers used many compounds, for example, Benzo[d][1,3]dioxol-4-ol (cas: 69393-72-2Application In Synthesis of Benzo[d][1,3]dioxol-4-ol).
Benzo[d][1,3]dioxol-4-ol (cas: 69393-72-2) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Application In Synthesis of Benzo[d][1,3]dioxol-4-ol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts