Microbial transformation of nitrogen-containing heterocyclic compounds. I. Hydroxylation of isomeric mono- and dimethylpyridines by microscopic fungi was written by Modyanova, L. V.;Vorob’eva, L. I.;Shibilkina, O. K.;Dovgilevich, E. V.;Terent’ev, P. B.;Kost, A. N.. And the article was included in Biotekhnologiya in 1990.HPLC of Formula: 102074-19-1 This article mentions the following:
By screening a number of museum microorganism cultures a group of microscopic fungi active in transforming mono- and dimethylpyridines was detected. It is only the Me substituent that undergoes oxidation, not the pyridine ring itself. Peculiarities of oxidative transformation of isomeric mono- and dimethylpyridines to the corresponding hydroxymethylpyridines were elucidated. For methylpyridines the pyridylcarbinol yield was independent of the Me substituent position. For dimethylpyridines only 1 Me group is subjected to hydroxylation, the ratio of the pyridylcarbinols obtained mainly depending on the substituent arrangement in the pyridine ring. In the experiment, the researchers used many compounds, for example, (5-Methylpyridin-3-yl)methanol (cas: 102074-19-1HPLC of Formula: 102074-19-1).
(5-Methylpyridin-3-yl)methanol (cas: 102074-19-1) belongs to alcohols. The oxygen atom of the strongly polarized O鈥旽 bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.HPLC of Formula: 102074-19-1
Referemce:
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Alcohols – Chemistry LibreTexts