Reaction of 2,6-lutidine 1-oxide with acetic anhydride was written by Kobayashi, Goro;Furukawa, Sunao;Kawada, Yuitsu. And the article was included in Yakugaku Zasshi in 1954.Application of 1122-71-0 This article mentions the following:
2,6-Lutidine 1-oxide (4 g.) in 15 ml. Ac2O heated 2 hrs. at 130-40掳, the Ac2O removed in vacuo, the residue with water concentrated in vacuo, made alk. with K2CO3, extracted with CHCl3 and distilled, gave 4 g. oil, b4 100-5掳. The oil in 10 ml. 10% HCl refluxed 30 min., the product concentrated in vacuo, made alk. with K2CO3, extracted with CHCl3 and distilled, gave 1.8 g. oil, and oxidation of the oil with KMnO4 gave 6,2-Me(HOH2C)C5H3N (I), m. 96掳; picrate, m. 129-32掳. I in C6H6 treated with PCl3 gave 6,2-Me(ClH2C)C5H3N (picrate, m. 162-3掳). The residue after distillation of I recrystallized from AcOEt gave 0.2 g. 2,6,3-Me2(HO)C5H2N, columns, m. 210-12掳. In the experiment, the researchers used many compounds, for example, 6-Methyl-2-pyridinemethanol (cas: 1122-71-0Application of 1122-71-0).
6-Methyl-2-pyridinemethanol (cas: 1122-71-0) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Application of 1122-71-0
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts