Production of (R)-1-phenylethanols through bioreduction of acetophenones by a new fungus isolate Trichothecium roseum was written by ilbeyaz, Kani;Taskin, Mesut;Kurbanoglu, Esabi B.;Kurbanoglu, Namudar I.;Kilic, Hamdullah. And the article was included in Chirality in 2010.COA of Formula: C8H9FO This article mentions the following:
A total of 120 fungal strains were isolated from soil samples and evaluated in the bioreduction of substituted acetophenones to the corresponding (R)-alcs. Among these strains, isolate Trichothecium roseum EBK-18 was highly effective in the production of (R)-alcs. with excellent enantioselectivity (ee > 99%). Gram scale preparation of (R)-1-phenylethanol is reported. Chirality 2010. 漏 2009 Wiley-Liss, Inc. In the experiment, the researchers used many compounds, for example, (S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4COA of Formula: C8H9FO).
(S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.COA of Formula: C8H9FO
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts