Use of Stille-type cross-coupling as a route to oligopyridylimines was written by Champouret, Yohan D. M.;Chaggar, Rajinder K.;Dadhiwala, Ishaq;Fawcett, John;Solan, Gregory A.. And the article was included in Tetrahedron in 2006.Related Products of 49669-14-9 This article mentions the following:
Tributylstannylpyridinyldioxolanes I (R = H, Me) are prepared; Stille coupling of I with bromopyridines in the presence of tetrakis(triphenylphosphine)palladium(0) followed by acid hydrolysis provides oligopyridinecarboxaldehydes and acetyloligopyridines such as II (R = H, Me) which are converted to arylimines such as III (R = H, Me; R1 = Me2CH). Lithiation of 2-(6-bromo-2-pyridinyl)-1,3-dioxolanes followed by alkylation with chlorotributylstannnane provides I (R = H, Me) in 88-92% yields. Stille coupling of I (R = H, Me) with bromopyridines such as 6,6′-dibromo-2,2′-bipyridine in the presence of tetrakis(triphenylphosphine)palladium(0) followed by hydrolysis with hydrochloric acid and neutralization provides oligopyridines such as quaterpyridines II (R = H, Me) in 45-80% yields; attempts to prepare a quinquepyridinedicarboxaldehyde by the same procedure yielded no isolable product because of the insolubility of the product formed upon deprotection. Aldehydes undergo condensation with 2,6-diisopropylaniline in ethanol in the presence of acetic acid to yield oligopyridineimines such as III (R = H; R1 = Me2CH), while acetyloligopyridines undergo condensation with 2,6-diisopropylaniline under solvent-free conditions at 160° in the presence of formic acid to yield imines such as III (R = Me; R1 = Me2CH). Crystal structures of III (R = H; R1 = Me2CH) and two other oligopyridylimines are determined by X-ray crystallog. In the experiment, the researchers used many compounds, for example, 2-Bromo-6-(2-methyl-1,3-dioxolan-2-yl)pyridine (cas: 49669-14-9Related Products of 49669-14-9).
2-Bromo-6-(2-methyl-1,3-dioxolan-2-yl)pyridine (cas: 49669-14-9) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Related Products of 49669-14-9
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts