Scope and limitations of montmorillonite K 10 catalyzed opening of epoxide rings by amines was written by Chakraborti, Asit K.;Kondaskar, Atul;Rudrawar, Santosh. And the article was included in Tetrahedron in 2004.HPLC of Formula: 40571-86-6 This article mentions the following:
Montmorillonite K 10 efficiently catalyzes the opening of epoxide rings by amines in high yields with excellent regio- and diastereoselectivities under solvent-free conditions at room temperature affording an improved process for synthesis of 2-amino alcs. Reaction of cyclohexene oxide with aryl/alkyl amines leads to the formation of trans-2-aryl/alkylaminocyclohexanols. For unsym. epoxides, the regioselectivity is controlled by the electronic and steric factors associated with the epoxide and the amine. Selective nucleophilic attack at the benzylic carbon of styrene oxide takes place with aromatic amines, whereas, aliphatic amines exhibit preferential nucleophilic attack at the terminal carbon. Aniline reacts selectively at the less hindered carbon of other unsym. epoxides. The difference in the internal strain energy of the epoxide ring in cycloalkene oxides and alkene oxides led to selective nucleophilic opening of cyclohexene oxide by aniline in the presence of styrene oxide. Due to the chelation effect, selective activation of the epoxide ring in 3-phenoxypropylene oxide takes place in the presence of styrene oxide leading to preferential cleavage of the epoxide ring in 3-phenoxypropylene oxide by aniline. In the experiment, the researchers used many compounds, for example, Trans-2-(benzylamino)cyclohexanol (cas: 40571-86-6HPLC of Formula: 40571-86-6).
Trans-2-(benzylamino)cyclohexanol (cas: 40571-86-6) belongs to alcohols. The oxygen atom of the strongly polarized O鈥旽 bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.HPLC of Formula: 40571-86-6
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts