2-(Trifluoromethyl)phenethyl alcohol (cas: 94022-96-5) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Computed Properties of C9H9F3O
Drug discovery based on the structure of FKBPs: design, synthesis and evaluation of L-1,4-thiazane-3-carboxylic acid derivatives as neuroimmunophilin ligands was written by Nie, Ai Hua;Xiao, Jun Hai;Liu, Hong Ying;Li, Li Wang;Li, Song. And the article was included in Chinese Chemical Letters in 2005.Computed Properties of C9H9F3O This article mentions the following:
Based on the structure of FK506, FKBP12 and calcineurin complex and the interactive characteristics of small mol. ligands with FK-506-binding proteins (FKBPs), a series of L-tetrahydro-1,4-thiazine-3-carboxylic acid derivatives I [X = O, R = PhCH2NMeCH2CH2, PhCH:CHCH2, 3-cyclohexylpropyl, 4-O2NC6H4CH2, etc.; X = NH, R = Me2CHCH2CH(CO2Et), PhCH2CH(CO2CH2Ph), etc.] was designed and synthesized as neuroimmunophilin ligands. The results of evaluation show that I [X = O; R = (PhCH2OCH2)2CH] (N308) has a great promise as a candidate of neuroprotective and neuroregenerative agent. In the experiment, the researchers used many compounds, for example, 2-(Trifluoromethyl)phenethyl alcohol (cas: 94022-96-5Computed Properties of C9H9F3O).
2-(Trifluoromethyl)phenethyl alcohol (cas: 94022-96-5) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Computed Properties of C9H9F3O
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts