Exploiting self-assembly for ligand-scaffold optimization: substrate-tailored ligands for efficient catalytic asymmetric hydroboration was written by Moteki, Shin A.;Takacs, James M.. And the article was included in Angewandte Chemie, International Edition in 2008.Formula: C8H9FO This article mentions the following:
A self-assembled ligand library (SAL XY) affords a wide range of R/S ratios in Rh-catalyzed asym. hydroboration. Ligand-scaffold optimization reveals substrate-tailored ligands that afford high regio- and enantioselectivity for a variety of ortho-substituted styrene derivatives In the experiment, the researchers used many compounds, for example, (S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4Formula: C8H9FO).
(S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Formula: C8H9FO
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts