Heterogeneous asymmetric hydrogenation of aromatic ketones enhanced by silanols on highly monodispersed silica spheres was written by Li, Chun;Zhang, Lin;Liu, Hailong;Zheng, Xueli;Fu, Haiyan;Chen, Hua;Li, Ruixiang. And the article was included in Catalysis Communications in 2014.HPLC of Formula: 171032-87-4 This article mentions the following:
A triphenylphosphine-stabilized Ir/SiO2 catalyst modified by a chiral diamine was synthesized with four silica spheres as support for the asym. hydrogenation of aromatic ketones. The H-bond between substrate and silanols and the interaction between substrate and modifier commonly affected the steric configuration of asym. hydrogenation of aromatic ketones. With the silanols increasing, the activity of asym. hydrogenation significantly increased. This is the first report of heterogeneous asym. hydrogenation of aromatic ketones enhanced by silanols on highly monodispersed silica spheres with > 99.9% ee and > 99% conversion. In the experiment, the researchers used many compounds, for example, (S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4HPLC of Formula: 171032-87-4).
(S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.HPLC of Formula: 171032-87-4
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts