Catalytic Hydroboration and Reductive Amination of Carbonyl Compounds by HBpin using a Zinc Promoter was written by Kumar, Ravi;Rawal, Parveen;Banerjee, Indrani;Pada Nayek, Hari;Gupta, Puneet;Panda, Tarun K.. And the article was included in Chemistry – An Asian Journal in 2022.Safety of (4-Chlorophenyl)methanol This article mentions the following:
The chemoselective hydroboration of aldehydes and ketones, catalyzed by Zinc(II) complexes [κ2-(PyCH:NR)ZnX2] (1, R = CPh3, X = Cl; 2, R = 2,6-iPr2C6H3, X = I), by pinacolborane (HBpin) at ambient temperature and under solvent-free conditions, which produced the corresponding borate esters in high yield, is reported. Zinc metal complexes 1 and 2 were derived in 80-90% yield from the reaction of iminopyridine [PyCH:NR] with anhydrous zinc dichloride in dichloromethane at room temperature The solid-state structures of both zinc complexes were confirmed using X-ray crystallog. Zinc complex 1 was also used as a competent pre-catalyst in the reductive amination of carbonyl compounds with HBpin under mild and solvent-free conditions to afford a high yield (up to 97%) of the corresponding secondary amines. The wider substrate scope of both reactions was explored. Catalytic protocols using zinc as a pre-catalyst demonstrated an atom-economic and green method with diverse substrates bearing excellent functional group tolerance. Computational studies established a plausible mechanism for catalytic hydroboration. In the experiment, the researchers used many compounds, for example, (4-Chlorophenyl)methanol (cas: 873-76-7Safety of (4-Chlorophenyl)methanol).
(4-Chlorophenyl)methanol (cas: 873-76-7) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Safety of (4-Chlorophenyl)methanol
Referemce:
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Alcohols – Chemistry LibreTexts