The chiral boronate-catalyzed asymmetric transfer hydrogenation of various aromatic ketones to high-value alcohols: Preparation and spectroscopic studies was written by Kilic, Ahmet;Durgun, Mustafa;Durap, Feyyaz;Aydemir, Murat. And the article was included in Journal of Organometallic Chemistry in 2019.COA of Formula: C4H11NO This article mentions the following:
The synthesis, spectroscopic studies and catalytic evaluation of the novel chiral salen ligands and their chiral boronate I and II [R = Bu, Ph, 3,5-difluoromethylphenyl, ferrocenyl] complexes was studied. Initially, the reaction of 5-azidomethyl salicylaldehyde and (R)-(-)-2-amino-1-butanol in absolute ethanol afforded a new chiral azide salen ligand. Then, a novel chiral salen ligand triazole derivative was prepared from chiral salen azide derivative for the synthesis of boronate complexes II through click reaction approach under ambient conditions. The reaction of chiral ligands with various boronic acids afforded a new tetra-coordinated mononuclear chiral boronate complexes I and II. All the compounds were remarkably stable crystalline solids and were obtained in good yields. For the full characterization of newly synthesized chiral salen ligands and their boronate complexes, the FT-IR, UV-Vis, NMR (1H, 13C and 11B), LC-MS and elemental anal. techniques were used. The well-shaped chiral boronate compounds were investigated as catalyst for the asym. transfer hydrogenation (ATH) of aromatic ketones under appropriate settings. Particularly, it was proved that the ferrocene-based boronate compounds afforded an efficient catalytic conversion compared to the other boronate complexes in the asym. transfer hydrogenation catalytic studies. In the experiment, the researchers used many compounds, for example, (R)-2-Aminobutan-1-ol (cas: 5856-63-3COA of Formula: C4H11NO).
(R)-2-Aminobutan-1-ol (cas: 5856-63-3) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.COA of Formula: C4H11NO
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts