Isolation, characterization and prediction of biological activity of two new fatty esters and a phenol from the heartwood of Pterocarpus Marsupium Roxb was written by Katiyar, Deepti;Singh, Vijender;Ali, Mohammed. And the article was included in International Journal of Pharmacy and Pharmaceutical Sciences in 2017.Application of 69393-72-2 This article mentions the following:
Objective: The current investigation involves the isolation, characterization and prediction of biol. activity spectra of the phytoconstituents from the ethanolic extract of the heartwood of Pterocarpus marsupium roxb. (Fabaceae). Methods: The heartwood (3 kg) was extracted in alc. by cold maceration for 21 d and the compounds were isolated by column chromatog. The compounds thus isolated were characterised and their structures were elucidated by using assorted spectral data anal., i.e., IR radiation spectroscopy (IR), proton NMR (1HNMR), carbon thirteen NMR (1C3 NMR) and direct anal. in real time mass spectrometry (DART-MS). PASS (prediction of activity spectra for substances) computer program was used to predict the biol. activity spectra of the isolated compounds Results: Phytochem. investigation of ethanolic extract of the heartwood of Pterocarpus marsupium led to isolate two fatty esters and a phenolic compound characterised as n-octanyl n-octadeca-9,12-dienoate (n-octanyl linoleiate, 1), n-dodecanyl n-octadeca-9,12-dienoate (n-dodecanyl linoleiate, 2) and 2, 3-dioxymethylene phenol (3). These phytoconstituents are reported for first time in the heartwood of Pterocarpus marsupium Roxb. The in silico profiling of these phytoconstituents exhibited their broad spectra of biol. activity. Compounds (1) and (2) showed their maximum activity as All-trans-retinyl-palmitate hydrolase inhibitor, anti eczematic, lipid metabolism regulator, etc. and compound (3) was found to be active as membrane integrity agonist, aspulvinone dimethylallyl transferases inhibitor, carminative, neurotransmitter uptake inhibitor, etc. Conclusion: These isolated phytoconstituents can be used as the marker compounds to establish the identity, quality and purity of the drug. The results of PASS prediction shall be very useful for establishing these phytoconstituents as active pharmacol. moieties. In the experiment, the researchers used many compounds, for example, Benzo[d][1,3]dioxol-4-ol (cas: 69393-72-2Application of 69393-72-2).
Benzo[d][1,3]dioxol-4-ol (cas: 69393-72-2) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Application of 69393-72-2
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts