Enantioselective hydrogenation of aromatic ketones: structural effects was written by Hess, Reto;Mallat, Tamas;Baiker, Alfons. And the article was included in Journal of Catalysis in 2003.Safety of (S)-1-(2-Fluorophenyl)ethanol This article mentions the following:
Enantioselective hydrogenation of acetophenone derivatives demonstrates the potential of the Pt-cinchona system in the synthesis of chiral alcs. that possess no functional group in the α-position to the CH-OH group. Electron-withdrawing functional groups in the aromatic ring increased the reaction rate and enantiomeric excess (ee), and the position of the group (o-, m-, or p-) was also important. In the hydrogenation of 3,5-di(trifluoromethyl)acetophenone under ambient conditions, 60% ee was obtained, though the special role of reaction parameters has not been investigated yet. Addition of cinchonidine slowed down all hydrogenation reactions-an unprecedented behavior for chirally modified Pt. In the experiment, the researchers used many compounds, for example, (S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4Safety of (S)-1-(2-Fluorophenyl)ethanol).
(S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Safety of (S)-1-(2-Fluorophenyl)ethanol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts