Ultrasound-promoted aminolysis of epoxides in aqueous media. A rapid procedure with no pH adjustment for additive-free synthesis of β-aminoalcohols was written by Abaee, M. Saeed;Hamidi, Vahid;Mojtahedi, Mohammad M.. And the article was included in Ultrasonics Sonochemistry in 2008.Formula: C13H19NO This article mentions the following:
An efficient and environmentally friendly procedure promoted by ultrasound irradiation was developed for stereoselective ring opening of various epoxides with aromatic and aliphatic amines under aqueous conditions in the presence of no catalyst or additive. Chemoselectivity of the protocol was shown by competition of piperidine and aniline to react with different epoxides resulting in exclusive formation of the resp. products of piperidine. In the experiment, the researchers used many compounds, for example, Trans-2-(benzylamino)cyclohexanol (cas: 40571-86-6Formula: C13H19NO).
Trans-2-(benzylamino)cyclohexanol (cas: 40571-86-6) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Formula: C13H19NO
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts