Dual Gold-Catalyzed Formal Tetradehydro-Diels-Alder Reactions for the Synthesis of Carbazoles and Indolines was written by Wang, Hong-Fa;Wang, Shi-Yue;Qin, Tian-Zhu;Zi, Weiwei. And the article was included in Chemistry – A European Journal in 2018.Application In Synthesis of (R)-2-Aminobutan-1-ol This article mentions the following:
A dual gold-catalyzed tetradehydro-Diels-Alder reaction was reported for the synthesis of indolines and carbazoles as well as other N-containing aromatic heterocycles, e.g., I, from yne-ynamides in high yields with good functional group tolerance. Unlike the traditional thermal tetradehydro-Diels-Alder reactions, diluted reaction concentration and radical prohibitors were not required for this protocol. Exptl. data supported a mechanism involving gold vinylidene species, which undergoes a 6 π electrocyclization, followed with 1,2-hydrogen shift. In the experiment, the researchers used many compounds, for example, (R)-2-Aminobutan-1-ol (cas: 5856-63-3Application In Synthesis of (R)-2-Aminobutan-1-ol).
(R)-2-Aminobutan-1-ol (cas: 5856-63-3) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Application In Synthesis of (R)-2-Aminobutan-1-ol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts