In situ formation of ligand and catalyst-application in ruthenium-catalyzed enantioselective reduction of ketones was written by Vaestilae, Patrik;Wettergren, Jenny;Adolfsson, Hans. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2005.Quality Control of (S)-1-(2-Fluorophenyl)ethanol This article mentions the following:
The direct in situ formation of highly efficient ruthenium-catalysts for the asym. reduction of ketones was obtained by combining chiral ligand building blocks with a ruthenium precursor. A catalyst was formed from a pseudo-dipeptide generated in situ from N-[(1,1-dimethylethoxy)carbonyl]-
(S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Quality Control of (S)-1-(2-Fluorophenyl)ethanol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts