Cu(I)-Catalyzed Microwave-Assisted Multicomponent Reaction Towards Synthesis of Diverse Fluorescent Quinazolino[4,3-b]quinazolin-8-ones and Their Photophysical Study was written by Pawar, Gaurav;Ghouse, Shaikh Mohammad;Joshi, Swanand Vinayak;Rana, Preeti;Kar, Swayamsiddha;Sarma, P. Mahesh;Dannarm, Srinivas Reddy;Sonti, Rajesh;Nanduri, Srinivas. And the article was included in ChemistrySelect in 2022.Synthetic Route of C7H7ClO This article mentions the following:
A novel, base- and ligand-free one pot protocol for the synthesis of fused-quinazolinone under microwave irradiation using environmentally friendly PEG-400 as a solvent has been developed. Besides benzaldehyde, various benzyl alcs. and Me arenes were used in this protocol, which extend its synthetic applicability. Photophys. study of this highly fluorescent framework was studied by fluorescent study. DFT and ESI/MS studies were carried out to justify the proposed mechanism. In the experiment, the researchers used many compounds, for example, (4-Chlorophenyl)methanol (cas: 873-76-7Synthetic Route of C7H7ClO).
(4-Chlorophenyl)methanol (cas: 873-76-7) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Synthetic Route of C7H7ClO
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts