Theoretical and experimental evidence for the action of terpenes as modulators in lung function was written by Zoenker, K. S.;Bluemel, G.;Probst, J.;Reiterer, W.. And the article was included in Progress in Respiration Research (1963-1994) in 1984.Application of 2451-01-6 This article mentions the following:
The terpenes tested (Pinocarveol [5947-36-4], Terpin hydrate [2451-01-6], Myrtenol [515-00-4], Myrtenal [564-94-3], Verbenone [80-57-9], and Trans-verbenol [1820-09-3]) all decreased the surface tension of a dipalmitoyllecithin monolayer and/or natural rat surfactant, indicating that if they could be placed at the air/water/lipid interface within the alveolar lining layer, they may be able to restore pulmonary function. In rabbits with natural tracheobronchial catarrhal effects, terpenes inhibited mucus secretion, decreased mucus deposition and increased the cilia-mediate mucus transport, indicating that terpenes may change the viscoelasticity of the mucus. In patients with chronic obstructive pulmonary disease, terpenes had variable effects. The use of the terpenes in patients with surfactant/lung function impairment is discussed. In the experiment, the researchers used many compounds, for example, rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6Application of 2451-01-6).
rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Application of 2451-01-6
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts