Regioselective ring opening of epoxides with amines using monodispersed silica nanoparticles in water was written by Sreedhar, B.;Radhika, P.;Neelima, B.;Hebalkar, Neha. And the article was included in Journal of Molecular Catalysis A: Chemical in 2007.Application of 40571-86-6 This article mentions the following:
Monodispersed silica nanoparticles were synthesized and used as catalyst for the regioselective synthesis of β-amino alcs. in water via nucleophilic ring opening of epoxides with amines under ambient conditions in shorter reaction times. The use of water as green solvent allows easy recycling of the catalyst. In the experiment, the researchers used many compounds, for example, Trans-2-(benzylamino)cyclohexanol (cas: 40571-86-6Application of 40571-86-6).
Trans-2-(benzylamino)cyclohexanol (cas: 40571-86-6) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Application of 40571-86-6
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts