Qualitative and quantitative characterization of monosaccharide components of Salvia miltiorrhiza, liguspyragine hydrochloride, and glucose injection was written by Ge, Fa-huan;Ma, Xian-peng;Ma, Jin-fang;Bi, Chang-qiong;Chen, Tian-ling;Zhang, Xiang-dong;Xiao, Xue. And the article was included in Journal of Analytical Methods in Chemistry in 2017.Application In Synthesis of (2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate This article mentions the following:
Salvia miltiorrhiza, liguspyragine hydrochloride, and glucose injection (SLGI) was made of Salvia miltiorrhiza Bge., liguspyragine hydrochloride, glucose, and glycerin. There were many kinds of monosaccharide components in SLGI, which might be from the raw material and Salvia miltiorrhiza Bge. Separation was performed on a Phenomenex Luna C18 anal. column (250mm × 4.6mmi.d., 5 μm, AccuStandard Inc., USA) at 30°C. The mobile phase consisted of two solvents: 0.1 mol/L phosphate-buffered saline (pH 6.7) (solvent A) and acetonitrile (solvent B) with gradient elution. The flow rate was maintained at 1.0 mL/min. Five kinds of monosaccharide components, glucose, D-mannose, L-rhamnose monohydrate, galactose, and xylose, were detected by precolumn derivatization HPLC, and their contents were compared with each other. And finally, concentrations of glucose in SLGI were determined and they were higher than the values of marked amount, which showed that one source of glucose might be from Salvia miltiorrhiza Bge. in SLGI. The average concentration of glucose was 5.18 g/100 mL, which was near the average value at 5.25 g/100mL detected by UV spectrophotometry and also close to the marked amount (5.00 g/100 mL) on the label. In the experiment, the researchers used many compounds, for example, (2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate (cas: 10030-85-0Application In Synthesis of (2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate).
(2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate (cas: 10030-85-0) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Application In Synthesis of (2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate
Referemce:
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