Efficient Aluminum Catalysts for the Chemical Conversion of CO2 into Cyclic Carbonates at Room Temperature and Atmospheric CO2 Pressure was written by Kim, Yoseph;Hyun, Kyunglim;Ahn, Duseong;Kim, Ran;Park, Myung Hwan;Kim, Youngjo. And the article was included in ChemSusChem in 2019.Safety of 1-(Dimethylamino)-2-methylpropan-2-ol This article mentions the following:
A series of dimeric aluminum compounds [Al(OCMe2CH2N(R)CH2X)]2 [X = pyridin-2-yl, R = H (PyrH); X = pyridin-2-yl, R = Me (PyrMe); X = furan-2-yl, R = H (FurH); X = furan-2-yl, R = Me (FurMe); X = thiophen-2-yl, R = H (ThioH); X = thiophen-2-yl, R = Me (ThioMe)] containing heterocyclic pendant group attached to the nitrogen catalyze the coupling of CO2 with epoxides under ambient conditions. In a comparison of their catalytic activities with those of aluminum complexes without pendant groups at N [X = H, R = H (HH); X = H, R = Me (HMe)] or with non-heterocyclic pendant groups [X = CH2CH2OMe, R = H(OMeH); X = CH2CH2NMe2, R =H(NMe2H); X = CH2CH2NMe2, R = Me (NMe2Me)], complexes containing heterocycles, in conjunction with (nBu)4NBr as a cocatalyst, showed higher catalytic activities for the synthesis of cyclic carbonates under the same ambient conditions. The best catalyst system for this reaction is PyrH/(nBu)4NBr system, which gives a turnover number of 99 and a turnover frequency of 4.1 h-1, making it 14- and 20-times more effective than HH/(nBu)4NBr and HMe/(nBu)4NBr, resp. Although there were no direct interactions between the aluminum and the heteroatoms in the heterocyclic pendants, electronic effects combined with the increased local concentration of CO2 around the active centers influences the catalytic activity in the coupling of CO2 with epoxides. In addition, PyrH/(nBu)4NBr showed broad epoxide substrate scope and seven terminal epoxides and two internal epoxides undergo the designed reaction. In the experiment, the researchers used many compounds, for example, 1-(Dimethylamino)-2-methylpropan-2-ol (cas: 14123-48-9Safety of 1-(Dimethylamino)-2-methylpropan-2-ol).
1-(Dimethylamino)-2-methylpropan-2-ol (cas: 14123-48-9) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Safety of 1-(Dimethylamino)-2-methylpropan-2-ol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts