Month: January 2023

Silk fibroin/polydopamine modified nanocapsules for high-performance adhesion was written by Xiao, Zuobing;Liu, Huiqin;Zhao, Qixuan;Niu, Yunwei;Zhao, Di. And the article was included in Colloids and Surfaces, A: Physicochemical and Engineering Aspects in 2022.Synthetic Route of C10H14O This article mentions the following:

In nature, aquatic organisms such as barnacles and mussels exhibit extraordinary underwater adhesion. Based on this, in this paper, silk fibroin (SF) and dopamine (DA) were mixed in an aqueous solution to obtain silk fibroin/polydopamine (SF-PDA) complex, and SiO₂ nanoparticles were prepared by sol-gel method. Then SiO₂ grafted SF-PDA was used as the wall material and carvacrol as the core material to obtain spherical structured nanocapsules (SSPM) with an average particle size of 332.60 nm. SF-PDA can generate double dynamic bonds, which can improve the crosslinking d. of SSPM with silk. The results showed that the residual rate of carvacrol in silk treated with SSPM and FeCl₃ solution was about 19.20% after 15 times washing cycles, while the residual rate of pure carvacrol-treated silk was only 0.42% at 10 times washing cycles, indicating that the nanocapsule has good washing durability. In vitro biocompatibility assessment of human skin cells confirmed that the cells were safe and non-toxic after 24 h exposure to treated silk. The handle test shows that the treated silk hardly affects the original touch and improves the added value of the silk. SF is extracted from silk waste, which reduces environmental pollution and contributes to the sustainable development of industry. Double dynamic bonding provides a simple and green strategy for the preparation of nanocomposites with potential applications in functional textiles, medical textiles, advanced functional materials, etc. In the experiment, the researchers used many compounds, for example, 5-Isopropyl-2-methylphenol (cas: 499-75-2Synthetic Route of C10H14O).

5-Isopropyl-2-methylphenol (cas: 499-75-2) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Synthetic Route of C10H14O

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Development of an Imine Chaperone for Selective C-H Functionalization of Alcohols via Radical Relay was written by Nakafuku, Kohki M.;Twumasi, Raymond K.;Vanitcha, Avassaya;Wappes, Ethan A.;Namitharan, Kayambu;Bekkaye, Mathieu;Nagib, David A.. And the article was included in Journal of Organic Chemistry in 2019.Electric Literature of C9H9F3O This article mentions the following:

The design of a radical relay chaperone to promote selective C-H functionalizations is described. A saccharin-based imine was found to be uniquely suited to effect C-H amination of alcs. via an in situ generated hemiaminal. This radical chaperone facilitates the mild generation of an N-centered radical while also directing its regioselective H atom transfer (HAT) to the β carbon of an alc. Upon β C-H halogenation, aminocyclization, and reductive cleavage, an NH₂ is formally added vicinal to an alc. The development, synthetic utility, and chemo-, regio-, and stereoselectivity of this imine chaperone-mediated C-H amination is presented herein. In the experiment, the researchers used many compounds, for example, 2-(Trifluoromethyl)phenethyl alcohol (cas: 94022-96-5Electric Literature of C9H9F3O).

2-(Trifluoromethyl)phenethyl alcohol (cas: 94022-96-5) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Electric Literature of C9H9F3O

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Determining the essential oil components and plant nutrient element values of some Satureja genotypes was written by Gedik, Osman;Kocabas, Yusuf Ziya;Cinar, Orcun. And the article was included in South African Journal of Botany in 2022.Reference of 3391-86-4 This article mentions the following:

The essential oil components and plant nutrient element values of a total of 4 different genotypes of two different species in the genus Satureja were determined in the present study. Nurhak, Baskonus, and Kapidere genotypes were classified as belonging to Satureja hortensis L., and Goksun genotype to Satureja cuneifolia Ten. The plant samples of the genotypes were taken during the flowering period, dried in the shade, and the resulting herbals were used for essential oil extraction and plant nutrient identification. The essential oil ratio among the genotypes was between 1.83-3.00% and the highest essential oil ratio was obtained from the Baskonus genotype with 3.00%. A total of 27 different components were determined in the essential oil of the genotypes, and the main components were found to be carvacrol (5.28-64.00%) and thymol (0.28-40.96%), -terpinene (17.23-32.36%), and cymene (7.78-16.80%). Regarding the plant nutrients, the highest Ca, Mn, Fe, and Mg values were found in Kapidere genotype; Zn, Na, and P in Baskonus genotype, K in Nurhak and Baskonus genotypes, and the highest Cu was detected in Nurhak genotype. Baskonus genotype stood out in terms of essential oil and carvacrol ratios. In the experiment, the researchers used many compounds, for example, Oct-1-en-3-ol (cas: 3391-86-4Reference of 3391-86-4).

Oct-1-en-3-ol (cas: 3391-86-4) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Reference of 3391-86-4

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ni-Catalyzed Enantioselective Reductive Diarylation of Activated Alkenes by Domino Cyclization/Cross-Coupling was written by Wang, Kuai;Ding, Zhengtian;Zhou, Zhijun;Kong, Wangqing. And the article was included in Journal of the American Chemical Society in 2018.COA of Formula: C12H16BBrO2 This article mentions the following:

A Ni-catalyzed enantioselective reductive diarylation of activated alkenes by domino cyclizative/cross-coupling of two aryl bromides is developed. This reaction proceeds under very mild conditions and shows broad substrate scope, without requiring the use of preformed organometallic reagents. Moreover, this approach provides direct access to various bis-heterocycles bearing all-carbon quaternary centers in synthetically useful yields (up to 81%) with excellent enantioselectivity (>30 examples, 90-99% ee). In the experiment, the researchers used many compounds, for example, 2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 68716-49-4COA of Formula: C12H16BBrO2).

2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 68716-49-4) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.COA of Formula: C12H16BBrO2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Identification of key residues in Debaryomyces hansenii carbonyl reductase for highly productive preparation of (S)-aryl halohydrins was written by Xu, Guo-Chao;Shang, Yue-Peng;Yu, Hui-Lei;Xu, Jian-He. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2015.Product Details of 120121-01-9 This article mentions the following:

Key residues of Debaryomyces hansenii carbonyl reductase in the determination of the reducing activity towards aryl haloketones were identified through combinatorial mutation of conserved residues. This study provides a green and efficient biocatalyst for the synthesis of (S)-aryl halohydrins. In the experiment, the researchers used many compounds, for example, (R)-1-(3-Chlorophenyl)ethanol (cas: 120121-01-9Product Details of 120121-01-9).

(R)-1-(3-Chlorophenyl)ethanol (cas: 120121-01-9) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Product Details of 120121-01-9

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

A pillar[6]arene-based UV-responsive supra-amphiphile: synthesis, self-assembly, and application in dispersion of multiwalled carbon nanotubes in water was written by Yang, Jie;Yu, Guocan;Xia, Danyu;Huang, Feihe. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2014.Recommanded Product: 60463-12-9 This article mentions the following:

A UV-responsive supra-amphiphile based on a water-soluble pillar[6]arene was constructed. Its self-assembly and application in dispersion of multi-walled carbon nanotubes in water were studied. In the experiment, the researchers used many compounds, for example, 3-(Hydroxymethyl)-4-nitrophenol (cas: 60463-12-9Recommanded Product: 60463-12-9).

3-(Hydroxymethyl)-4-nitrophenol (cas: 60463-12-9) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Recommanded Product: 60463-12-9

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

A comparative and mechanistic study on regioselective photooxidative demethylation of N-heterocyclics using TiO₂ and molecular oxygen was written by Rao, Kambala V. Subba;Srinivas, Basavaraju;Boule, Pierre;Subrahmanyam, Machiraju. And the article was included in Journal of Chemical Technology and Biotechnology in 2002.Name: 6-Methyl-2-pyridinemethanol This article mentions the following:

Regioselective photooxidative demethylation of methyl-substituted N-containing heterocyclic compounds is investigated in non-aqueous (ethane nitrile) solutions containing semiconductor oxide (TiO₂) as photocatalyst in the presence of mol. oxygen upon irradiation at room temperature conditions. A plausible electron transfer mechanism, in which an electron-hole pair is generated on the surface of TiO₂ by illumination, is proposed for the semiconductor-mediated photocatalysis. MO calculation by the AM 1 method has been performed for the electron densities of N-atoms of heterocyclics in the present study. In the experiment, the researchers used many compounds, for example, 6-Methyl-2-pyridinemethanol (cas: 1122-71-0Name: 6-Methyl-2-pyridinemethanol).

6-Methyl-2-pyridinemethanol (cas: 1122-71-0) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Name: 6-Methyl-2-pyridinemethanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Light-controllable chiral dopant based on azo-fragment: synthesis and characterisation was written by Chornous, V.;Vovk, M.;Bratenko, M.;Dmytriv, Yu.;Rudnichenko, A.;Skorobahatko, M.;Kasian, N.;Lisetski, L.;Gvozdovskyy, I.. And the article was included in Liquid Crystals in 2022.HPLC of Formula: 2216-51-5 This article mentions the following:

The synthesis of chiral dopant 2-[(2-isopropyl-5-methylcyclohexyl)oxy]-2-oxoethyl 4-{(E)-[4-(decyloxy)phenyl]diazenyl}benzoate (ChD-3501), consisting of azo- and aliphatic fragments together with a chiral center based on L-menthol as a reversible light-controllable chiral dopant was presented. To assess the effects of UV-vis irradiation and temperature in the isotropic and liquid crystalline (LC) states, the spectral kinetics of ethanol solution of ChD-3501, as well as induction of the cholesteric helix when it was dissolved in nematic LC (E7) as a chiral dopant was studied. The concentration dependence of the helical pitch of the induced cholesterics was studied by means on Grandjean-Cano method, and the helical twisting power of ChD-3501 in the nematic host E7 was determined The reversible trans-cis isomerisation of chiral dopant ChD-3501 in E7 under UV-vis irradiation was studied, and it was found that the storage of the cis-isomer at certain constant temperature also leads to the reversible isomerisation. Possible applications of the studied system were discussed. In the experiment, the researchers used many compounds, for example, (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5HPLC of Formula: 2216-51-5).

(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.HPLC of Formula: 2216-51-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Alcohol-initiated dediazoniation of aryldiazonium ions to aryl radicals: a simple and efficient route to arylboronates was written by Zhang, Xiulian;Zhang, Zhicheng;Xie, Yongbin;Jiang, Yujie;Xu, Ruibo;Luo, Yuhui;Tao, Chuanzhou. And the article was included in Journal of Chemical Research in 2018.Reference of 68716-49-4 This article mentions the following:

A simple and efficient access to arylboronates was achieved with methanol-initiated borylation of aryldiazonium salts. Reduction of aryldiazonium ions by single electron transfer from methanol affords aryl radical species, which undergo a subsequent C-B bond formation with bis(pinacolato)diboron. This highly practical borylation process, which can be carried out on the gram-scale, enjoys operational simplicity as well as mild and catalyst-free conditions. In the experiment, the researchers used many compounds, for example, 2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 68716-49-4Reference of 68716-49-4).

2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 68716-49-4) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Reference of 68716-49-4

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Asymmetric reduction of substituted acetophenones using once immobilized Rhodotorula glutinis cells was written by Kurbanoglu, Esabi B.;Zilbeyaz, Kani;Ozdal, Murat;Taskin, Mesut;Kurbanoglu, Namudar I.. And the article was included in Bioresource Technology in 2010.Name: (S)-1-(2-Fluorophenyl)ethanol This article mentions the following:

The asym. reductions of acetophenone and its analogs using once immobilized Rhodotorula glutinis cells were studied. The performance and reaction parameters of the immobilized cells were also investigated and it was determined that the cells could be used 15 times in batch processes. All chiral alcs. obtained using purification procedures were of sufficient enantiopurity (>99%) of the (S)-enantiomer. The applicability of the optimized process for a preparative scale bioreduction was shown. Under the optimum conditions, 35 mM (4.3 g) of the product ((S)-1-phenylethanol) was produced from 45 mM (5.4 g) of the substrate (acetophenone) with one time immobilized R. glutinis EBK-2 cells (6 g wet weight). The yield was calculated as 77%. In this study, it was found that the buffer level had a very significant effect on the reaction activity. Our results demonstrate that the optimized process can be implemented on a preparative scale. In the experiment, the researchers used many compounds, for example, (S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4Name: (S)-1-(2-Fluorophenyl)ethanol).

(S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Name: (S)-1-(2-Fluorophenyl)ethanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts