Rasoolzadeh, Ali et al. published their research in Journal of Natural Gas Science and Engineering in 2022 | CAS: 111-46-6

2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Product Details of 111-46-6

Determination of clathrate hydrates dissociation conditions in the presence of gas dehydration, sweetening, and other nitrogenated additives using a predictive thermodynamic approach was written by Rasoolzadeh, Ali;Bakhtyari, Ali;Mehrabi, Khayyam;Javanmardi, Jafar;Nasrifar, Khashayar;Mohammadi, Amir H.. And the article was included in Journal of Natural Gas Science and Engineering in 2022.Product Details of 111-46-6 This article mentions the following:

Despite numerous exptl. data on gas hydrate equilibrium conditions in the presence of glycols, alkanolamines, and nitrogenated additives that are frequently utilized in the gas refinery, the apparent lack of a precise predictive thermodn. model is still perceived. This study presents an unprecedented thermodn. framework benefitting from the modified van der Waals-Platteeuw (vdW-P) model for the hydrate phase, the Peng-Robinson equation of state (PR EoS) for the vapor/gas phase, and combinations of free-volume Flory Huggins (FVFH) and Pitzer-Debye-Huckel (PDH) equations for the water activity in the aqueous phase, in which the FVFH activity model is utilized for the additives with mol. interactions solely, while the PDH model is employed when the ionic interactions also exist. When the model assessed a databank of 1075 data points, 0.29% (0.80 K) and 9.67% (0.49 MPa) deviations were observed in the temperature and pressure calculations, resp. In particular, for 877 data points (glycols, urea, acetamide, and formamide), employing FVFH solely resulted in 0.32% (0.88 K) and 10.54% (0.50 MPa) temperature and pressure deviations, resp., whereas the combination of FVFH + PDH yielded 0.17% (0.48 K) and 5.81% (0.47 MPa) errors in temperature and pressure estimations, resp. in 198 data points of the systems comprised of amines, hydrazine, and piperazine. The maximum deviation of temperature prediction did not exceed 6.80 K (2.39%). The results reveal the effective performance of the proposed calculation approach. In the experiment, the researchers used many compounds, for example, 2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6Product Details of 111-46-6).

2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Product Details of 111-46-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Naik, Ravi et al. published their research in ACS Chemical Neuroscience in 2018 | CAS: 118289-16-0

2-Bromopyridine-4-methanol (cas: 118289-16-0) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Application In Synthesis of 2-Bromopyridine-4-methanol

Synthesis and Evaluation of a New 18F-Labeled Radiotracer for Studying the GABAB Receptor in the Mouse Brain was written by Naik, Ravi;Valentine, Heather;Dannals, Robert F.;Wong, Dean F.;Horti, Andrew G.. And the article was included in ACS Chemical Neuroscience in 2018.Application In Synthesis of 2-Bromopyridine-4-methanol This article mentions the following:

New GABAB agonists, fluoropyridyl ether analogs of baclofen, have been synthesized as potential PET radiotracers. The compound with highest inhibition binding affinity as well as greatest agonist response, (R)-4-amino-3-(4-chloro-3-((2-fluoropyridin-4-yl)methoxy)phenyl)butanoic acid (1b), was radiolabeled with 18F with good radiochem. yield, high radiochem. purity, and high molar radioactivity. The regional brain distribution of the radiolabeled (R)-4-amino-3-(4-chloro-3-((2-[18F]fluoropyridin-4-yl)methoxy)phenyl)butanoic acid, [18F]1b, was studied in CD-1 male mice. The study demonstrated that [18F]1b enters the mouse brain (1% ID/g tissue). The accumulation of [18F]1b in the mouse brain was inhibited (35%) by preinjection of GABAB agonist 1a, suggesting that the radiotracer brain uptake is partially mediated by GABAB receptors. The presented data demonstrate a feasibility of imaging of GABAB receptors in rodents and justify further development of GABAB PET tracers with improved specific binding and greater blood-brain barrier permeability. In the experiment, the researchers used many compounds, for example, 2-Bromopyridine-4-methanol (cas: 118289-16-0Application In Synthesis of 2-Bromopyridine-4-methanol).

2-Bromopyridine-4-methanol (cas: 118289-16-0) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Application In Synthesis of 2-Bromopyridine-4-methanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yoshida, Mia et al. published their research in European Journal of Pharmaceutics and Biopharmaceutics in 2017 | CAS: 109-17-1

((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate) (cas: 109-17-1) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Product Details of 109-17-1

Complexation hydrogels as potential carriers in oral vaccine delivery systems was written by Yoshida, Mia;Kamei, Noriyasu;Muto, Keiya;Kunisawa, Jun;Takayama, Kozo;Peppas, Nicholas A.;Takeda-Morishita, Mariko. And the article was included in European Journal of Pharmaceutics and Biopharmaceutics in 2017.Product Details of 109-17-1 This article mentions the following:

Most current vaccine preparations are in injectable forms, which are inconvenient to patients and ineffective in mucosal immunization. Therefore, most research in this field has been directed at developing ideal oral vaccines enabling the induction of both systemic and mucosal immune responses. In the present study, we examined the utility of a pH-responsive polymeric carrier, poly (methacrylic acid-g-ethylene glycol) [P (MAA-g-EG)] hydrogel, as a potential oral vaccine carrier that can protect cargo proteins in the gastrointestinal tract. Ovalbumin (OVA) and cholera toxin (CT) were first used as the model antigen and mucosal adjuvant, resp. In vitro incorporation and releasing studies demonstrated that approx. 30% of both OVA and CT were entrapped in the P(MAA-g-EG) hydrogel, and the release of such proteins from the hydrogel to the media was pH-dependent. In vivo oral administration of an OVA-loaded hydrogel (OVA-LP) with either CT or a CT-loaded hydrogel (CT-LP) to rats increased the levels of anti-OVA IgG in the plasma. Furthermore, when CT-LP was orally administered to mice as an antigen, both anti-CT IgG in the plasma and IgA in the fecal extract were detected. These results indicated that the P(MAA-g-EG) hydrogel is a promising and useful carrier for developing oral vaccine delivery systems. In the experiment, the researchers used many compounds, for example, ((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate) (cas: 109-17-1Product Details of 109-17-1).

((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate) (cas: 109-17-1) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Product Details of 109-17-1

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kasmuri, Norhafezah et al. published their research in Environmental Science and Pollution Research in 2022 | CAS: 111-46-6

2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Application In Synthesis of 2,2′-Oxybis(ethan-1-ol)

Occurrence, impact, toxicity, and degradation methods of microplastics in environment-a review was written by Kasmuri, Norhafezah;Tarmizi, Nur Aliah Ahmad;Mojiri, Amin. And the article was included in Environmental Science and Pollution Research in 2022.Application In Synthesis of 2,2′-Oxybis(ethan-1-ol) This article mentions the following:

Microplastic defines as a tiny plastic particle that has a size of less than 5 mm and is ubiquitous in the environment. Due to the tiny size, this microplastic adversely affected the environment, notably aquatic life via ingestion, choking, and entanglement. This microplastic is arduous to degrade as it takes a thousand years due to the properties of plastic itself and consequently remains in nature. In dealing with microplastic issues, this paper reflects the occurrence, impact, toxicity, and degradation methods of microplastics in the environment including phys., chem., and biol. treatments. Here, the phys. treatment methods include incineration treatment, UV, and photocatalytic. The incineration process contributes to environmental pollution due to the release of toxic gases into the atm. In addition, chem. treatments for plastic waste are the degradation process involving chem. additives such as ethylene glycol (EG), nano-magnesium oxide (MgO), diethylene glycol (DEG), and calcium or zinc (Ca/Zn) stearate as a catalyst. These treatments depend on the chems. that can affect human health and the ecosystem. The biodegradation treatment using bacterial and fungal species can consume the microplastic without disrupting the surrounding environment and biota. It includes recent findings on the biodegradation of microplastic under aerobic and anaerobic conditions. Thus, biodegradation can be considered the best option to degrade microplastic as green and sustainable technol. In the experiment, the researchers used many compounds, for example, 2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6Application In Synthesis of 2,2′-Oxybis(ethan-1-ol)).

2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Application In Synthesis of 2,2′-Oxybis(ethan-1-ol)

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Serrenho, R. Couto et al. published their research in Journal of Dairy Science in 2022 | CAS: 57-55-6

1,2-Propanediol (cas: 57-55-6) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Product Details of 57-55-6

An investigation of blood, milk, and urine test patterns for the diagnosis of ketosis in dairy cows in early lactation was written by Serrenho, R. Couto;Williamson, M.;Berke, O.;LeBlanc, S. J.;DeVries, T. J.;McBride, B. W.;Duffield, T. F.. And the article was included in Journal of Dairy Science in 2022.Product Details of 57-55-6 This article mentions the following:

Ketosis in dairy cattle is primarily diagnosed based on the concentrations of ketone bodies in the blood, milk, or urine. Cow-side tests using these fluids are available for rapid detection of elevated concentrations of ketone bodies. Although these tests have been extensively validated, the performance of different tests has not been compared over time. Our objectives were to investigate the relationship between point-of-care diagnostic tests measuring the concentrations of β-hydroxybutyrate (BHB) in blood (BT; Precision Xtra, Abbott Laboratories), BHB in milk (MT; Keto-Test, Elanco), and acetoacetate (AcAc) in urine (UT; Ketostix, Bayer Corporation) through cases of ketosis. Holstein cows (n = 148) were screened daily for hyperketonemia (HYK; blood BHB ≥1.2 mmol/L) from 3 to 16 d in milk (DIM); moreover, milk and urine samples were collected concomitantly and tested for ketones (ketosis thresholds: 100μmol/L milk BHB and 5 mg/dL urine AcAc). Of the animals screened (n = 148), 74% were diagnosed with HYK. When diagnosed with HYK, cows were treated with propylene glycol orally once daily for 5 d. After the day of diagnosis (d 0), hyperketonemic cows were retested with BT, MT, and UT for 3 d (d 1, 2, and 3). We assessed the diagnostic test performance and time to ketosis (survival analyses and Cox proportional hazards models) of MT and UT compared with BT. Considering all paired samples (before and after diagnosis of HYK), MT had 61% sensitivity and 91% specificity, whereas the UT had 77% sensitivity and 94% specificity compared with BT. The specificity of MT and UT increased from d 0 to d 1, decreased on d 2, and increased on d 3. The median time to diagnosis of ketosis in blood was 5 DIM (95% CI 5 to 7 DIM); moreover, MT and UT had 2 d greater median time to diagnosis of ketosis compared with the BT [7 DIM (6 to 11 d); and 7 DIM (6 to 13 d), resp.]. We concluded that the UT is a more sensitive predictor of blood BHB concentration than the MT. The UT and MT tests diagnosed ketotic cows approx. 2 d later than the BT. The possible consequences of delay in detection of ketosis in milk and urine should be investigated. In the experiment, the researchers used many compounds, for example, 1,2-Propanediol (cas: 57-55-6Product Details of 57-55-6).

1,2-Propanediol (cas: 57-55-6) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Product Details of 57-55-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Lei, Yong et al. published their research in Aquaculture in 2021 | CAS: 137-08-6

Calcium (R)-3-(2,4-dihydroxy-3,3-dimethylbutanamido)propanoate (cas: 137-08-6) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Application In Synthesis of Calcium (R)-3-(2,4-dihydroxy-3,3-dimethylbutanamido)propanoate

Effect of dietary phosphorus on growth performance, body composition, antioxidant activities and lipid metabolism of juvenile Chinese mitten crab (Eriocheir sinensis) was written by Lei, Yong;Sun, Yanfang;Wang, Xiaodan;Lin, Zhideng;Bu, Xianyong;Wang, Nan;Du, Zhenyu;Qin, Jianguang;Chen, Liqiao. And the article was included in Aquaculture in 2021.Application In Synthesis of Calcium (R)-3-(2,4-dihydroxy-3,3-dimethylbutanamido)propanoate This article mentions the following:

This study investigated the effects of dietary phosphorus (P) on growth, body composition, antioxidant activities and lipid metabolism of juvenile Chinese mitten crab (Eriocheir sinensis). Six diets containing available P levels at 0.20%, 0.44%, 0.99%, 1.37%, 1.75% and 2.01% were prepared and fed to juvenile E. sinensis (0.38 ± 0.01 g) for 56 days. The weight gain, specific growth rate and molting frequency were markedly affected by dietary P, and the highest weight gain and specific growth rate were obtained in crabs fed the 0.99% available P diet. With increasing the dietary available P levels, the whole-body ash, Ca, and P contents, as well as the hepatopancreas and serum P contents increased, while the whole-body Mg content decreased. The increase of dietary P levels significantly decreased the lipid contents of whole-body, hepatopancreas and muscle, while increased the crude protein content of hepatopancreas. The hepatopancreas and serum alk. phosphatase activities increased with an increase in dietary available P levels from 0.20% to 1.37%, and then decreased afterward. The crabs fed 1.37% available P diet had a markedly higher alk. phosphatase activity than those fed 0.20%, 0.44% and 2.01% available P diets. Moreover, dietary P significantly affected total antioxidant capacity, the activities of total superoxide dismutase and glutathione peroxidase, and the malondialdehyde content in the hepatopancreas. The highest antioxidant activity and lowest malondialdehyde content in the hepatopancreas were found in the crabs fed 1.37% of available P in the diet. The relative mRNA expression showed that dietary P reduced hepatopancreas lipid accumulation might be produced through suppressing the genes related to lipid synthesis and promoting the genes related to lipid transport. This study demonstrates that optimum dietary P could enhance growth, antioxidant capacity and reduce hepatopancreatic lipid accumulation in juvenile E. sinensis and the range of available P in the diet is suggested to be 1.16%-1.51%. In the experiment, the researchers used many compounds, for example, Calcium (R)-3-(2,4-dihydroxy-3,3-dimethylbutanamido)propanoate (cas: 137-08-6Application In Synthesis of Calcium (R)-3-(2,4-dihydroxy-3,3-dimethylbutanamido)propanoate).

Calcium (R)-3-(2,4-dihydroxy-3,3-dimethylbutanamido)propanoate (cas: 137-08-6) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Application In Synthesis of Calcium (R)-3-(2,4-dihydroxy-3,3-dimethylbutanamido)propanoate

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Gutierrez-Sanchez, Pablo et al. published their research in Separation and Purification Technology in 2022 | CAS: 499-75-2

5-Isopropyl-2-methylphenol (cas: 499-75-2) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Computed Properties of C10H14O

Extraction of neonicotinoid pesticides from aquatic environmental matrices with sustainable terpenoids and eutectic solvents was written by Gutierrez-Sanchez, Pablo;Navarro, Pablo;Alvarez-Torrellas, Silvia;Garcia, Juan;Larriba, Marcos. And the article was included in Separation and Purification Technology in 2022.Computed Properties of C10H14O This article mentions the following:

The potential environmental impact and adverse effects of the occurrence of pesticides in the aquatic environment have raised great social and political concern, leading to their control by means of several regulations, such as the European Directive 98/83/EC. In this regard, the three neonicotinoid pesticides analyzed in this work (acetamiprid, imidacloprid, and thiamethoxam) have been included in the surface water European Watch Lists under the Water Framework Directive. This research proposes the use of terpenoid-based solvents for the extraction of the three emerging contaminants previously mentioned. An initial screening of the extraction solvents was carried out through the COSMO-RS methodol., selecting the most favorable pure terpenes, eutectic terpenoid-based and conventional solvents. Furthermore, relevant issues were exptl. analyzed, such as extraction in more realistic multicomponent mixtures together with key parametric studies covering operating temperature and matrix influence. Carvacrol, a pure terpenoid not applied before as an extraction solvent of pesticides, has been revealed as an effective and sustainable substitute for conventional solvents for the first time to the best of our knowledge. Specifically, carvacrol exhibited overall extraction yields of around 97.5% from a river water matrix at a volumetric S/F ratio of 0.1 and 303.2 K. High extraction yields from river water matrixes regardless of temperature pointed to the potential of this solvent for a wide range of industrial application. In the experiment, the researchers used many compounds, for example, 5-Isopropyl-2-methylphenol (cas: 499-75-2Computed Properties of C10H14O).

5-Isopropyl-2-methylphenol (cas: 499-75-2) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Computed Properties of C10H14O

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Palmer, Andreas M. et al. published their research in Journal of Medicinal Chemistry in 2010 | CAS: 142253-56-3

1-Boc-Azetidine-3-yl-methanol (cas: 142253-56-3) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Category: alcohols-buliding-blocks

Tetrahydrochromenoimidazoles as Potassium-Competitive Acid Blockers (P-CABs): Structure – Activity Relationship of Their Antisecretory Properties and Their Affinity toward the hERG Channel was written by Palmer, Andreas M.;Chiesa, Vittoria;Schmid, Anja;Muench, Gabriela;Grobbel, Burkhard;Zimmermann, Peter J.;Brehm, Christof;Buhr, Wilm;Simon, Wolfgang-Alexander;Kromer, Wolfgang;Postius, Stefan;Volz, Jurgen;Hess, Dietmar. And the article was included in Journal of Medicinal Chemistry in 2010.Category: alcohols-buliding-blocks This article mentions the following:

Potassium-competitive acid blockers constitute a new therapeutic option for the treatment of acid-related diseases that are widespread and constitute a significant economical burden. Enantiomerically pure (tetrahydro)chromenoimidazoles I [R1 = 2-MeC6H4, R2 = Et, R3 = H; R1 = 2-(c-C3H5)C6H4, R2 = R3 = Me, etc.] were prepared using either the readily available candidate I (R1 = 2-MeC6H4, R2 = R3 = Me) as starting material or where the Noyori asym. reduction of ketones, e.g., II, was the key reaction. A comprehensive SAR regarding the influence of the 5-carboxamide and the 8-aryl residue on in vitro activity, acid-suppression in the Ghosh Schild rat, and affinity toward the hERG channel was established. In addition, efficacy and duration of the antisecretory action was examined for the most promising target compounds by 24 h pH-metry in the fistula dog and a significantly different SAR was observed as compared to the Ghosh Schild rat. Several (tetrahydro)chromenoimidazoles were identified that possessed a comparable profile as the candidate I (R1 = 2-MeC6H4, R2 = R3 = Me). In the experiment, the researchers used many compounds, for example, 1-Boc-Azetidine-3-yl-methanol (cas: 142253-56-3Category: alcohols-buliding-blocks).

1-Boc-Azetidine-3-yl-methanol (cas: 142253-56-3) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Category: alcohols-buliding-blocks

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Elbing, Mark et al. published their research in Advanced Functional Materials in 2008 | CAS: 29364-29-2

Sodium 2-methyl-2-propanethiolate (cas: 29364-29-2) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Recommanded Product: 29364-29-2

Single component self-assembled monolayers of aromatic azo-biphenyl: influence of the packing tightness on the SAM structure and light-induced molecular movements was written by Elbing, Mark;Blaszczyk, Alfred;von Haenisch, Carsten;Mayor, Marcel;Ferri, Violetta;Grave, Christian;Rampi, Maria Anita;Pace, Giuseppina;Samori, Paolo;Shaporenko, Andrei;Zharnikov, Michael. And the article was included in Advanced Functional Materials in 2008.Recommanded Product: 29364-29-2 This article mentions the following:

Aiming at modulating the packing d. within functional self-assembled monolayers (SAMs), two azo-biphenyl derivatives AZO1 and AZO2 comprising a terminal sulfur anchor group have been designed and synthesized. While AZO1 allows for a coplanar arrangement of both biphenyl subunits, addnl. steric repulsion due to two Me side groups attached to the footing biphenyl of AZO2 results in an increased intermol. distance within the SAM, providing addnl. free volume SAMs of both derivatives on gold and platinum substrates have been formed and thoroughly investigated by photoelectron (XPS) and near-edge absorption fine structure (NEXAFS) spectroscopy as well as cyclic voltammetry and scanning tunneling microscopy. These measurements confirmed the formation of tightly packed SAMs for AZO1, while AZO2 formed SAMs consisting of less organized and more loosely packed mols. Optical investigations of both azo derivatives in solution as well as their SAMs displayed efficient photoisomerization in solution and in SAMs. Comparable maximal cis/trans ratios of ca. 0.9 have been observed in all cases upon irradiation at λ = 370 and 360 nm for AZO1 and AZO2, resp. The thermally induced cis → trans back reaction on AZO1 was found to be slower by a factor of 3 in SAMs as compared to solution, while AZO2 displayed comparable rates of the back reaction in both environments. This behavior can be explained by the different nature of mol. isomerization in the two SAM systems: whereas the isomerization in AZO1 SAMs takes place in a highly coordinated, collective way and involves many adjacent mols., AZO2 species behave rather individually even packed in SAMs, such that their isomerization process is similar in SAMs and in solutions In the experiment, the researchers used many compounds, for example, Sodium 2-methyl-2-propanethiolate (cas: 29364-29-2Recommanded Product: 29364-29-2).

Sodium 2-methyl-2-propanethiolate (cas: 29364-29-2) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Recommanded Product: 29364-29-2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Das, Saikat et al. published their research in Angewandte Chemie, International Edition in 2018 | CAS: 5856-63-3

(R)-2-Aminobutan-1-ol (cas: 5856-63-3) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Recommanded Product: (R)-2-Aminobutan-1-ol

Chiral Recognition and Separation by Chirality-Enriched Metal-Organic Frameworks was written by Das, Saikat;Xu, Shixian;Ben, Teng;Qiu, Shilun. And the article was included in Angewandte Chemie, International Edition in 2018.Recommanded Product: (R)-2-Aminobutan-1-ol This article mentions the following:

Endowed with chiral channels and pores, chiral metal-organic frameworks (MOF) are highly useful; however, their synthesis is a challenge since most chiral building blocks are expensive. Although MOF with induced chirality have been reported to avoid this shortcoming, no study providing evidence for the ee value of such MOF has yet been reported. This is the first study to describe the efficiency of chiral induction in MOF using inexpensive achiral building blocks and fully recoverable chiral dopants to control the handedness of racemic MOF. This method yielded chirality-enriched MOF with accessible pores. The ability of the materials to form host-guest complexes was probed with enantiomers of varying size and coordination and in solvents with varying polarity. Mixed-matrix membranes comprised of chirality-enriched MOF particles dispersed in a polymer matrix demonstrated a new chiral separation route. In the experiment, the researchers used many compounds, for example, (R)-2-Aminobutan-1-ol (cas: 5856-63-3Recommanded Product: (R)-2-Aminobutan-1-ol).

(R)-2-Aminobutan-1-ol (cas: 5856-63-3) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Recommanded Product: (R)-2-Aminobutan-1-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts