Fe(III)-catalyzed trityl benzyl ether formation and disproportionation cascade reactions to yield benzaldehydes was written by Wang, Xiaoyu;Du, Chuan;Shi, Hui;Pang, Yadong;Jin, Shengfei;Hou, Yuqian;Wang, Yanshi;Peng, Xiaoshi;Xiao, Jianyong;Liu, Yang;Liu, Yongxiang;Cheng, Maosheng. And the article was included in Tetrahedron in 2015.Formula: C7H6BrClO This article mentions the following:
During investigating water-compatible Lewis acids catalyzed etherifications using alcs. as alkylating reagents directly, Fe(III)-catalyzed trityl benzyl ether formations irradiated by microwave are developed. Then an in situ trityl benzyl ether formation and disproportionation cascade reaction was achieved to yield the benzaldehyde products with good functional group tolerances under neat conditions at relative higher temperatures The substituent effects of the substrates on the etherification and disproportionation were explored by changing the substitutions on benzyl alcs. and triarylmethanols using chem. kinetic plots methods and the mechanism of the transformation was studied by crossover experiments The etherification and disproportionation cascade process could be conveniently scaled up in laboratory without losing much efficiency. In the experiment, the researchers used many compounds, for example, (2-Bromo-5-chlorophenyl)methanol (cas: 60666-70-8Formula: C7H6BrClO).
(2-Bromo-5-chlorophenyl)methanol (cas: 60666-70-8) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Formula: C7H6BrClO
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts