The versatile, efficient, and stereoselective self-assembly of transition-metal helicates by using hydrogen-bonds was written by Telfer, Shane G.;Kuroda, Reiko. And the article was included in Chemistry – A European Journal in 2005.Electric Literature of C7H9NO This article mentions the following:
A diverse range of dinuclear double-stranded helicates in which the ligand strand is built up by using H-bonding was synthesized. The helicates, formulated as [Co2(L)2(L-H)2X2], readily self-assemble from a mixture of a suitable pyridine-alc. compound (L; for example, 6-methylpyridine-2-methanol, 1), and a CoX2 salt in the presence of base. Nine such helicates were characterized by x-ray crystallog. For helicates derived from the same pyridine-alc. precursor, a remarkable regularity was found for both the mol. structure and the crystal packing arrangements, regardless of the nature of the ancillary ligand (X). A notable exception was observed in the solid-state structure of [Co2(1)2(1-H)2(NCS)2] for which intermol. nonbonded contacts between the S atoms (S···S = 3.21 Å) give 1-dimensional chains. Helicates derived from (R)-6-methylpyridine-2-methanol (2) are soluble in solvents such as MeCN and CH2Cl2, and their self-assembly could be monitored in solution by 1H NMR, UV/visible, and CD titrations No intermediate complexes form in a significant concentration at any point throughout these titrations The global thermodn. stability constant of [Co2(2)2(2-H)2(NO3)2] was calculated from spectrophotometric data to be logβ = 8.9(8). The stereoisomerism of these helicates was studied in some detail and the self-assembly process is highly stereoselective. The chirality of the ligand precursors can control the absolute configuration of the metal centers and thus the overall helicity of the dinuclear assemblies. Also, the enantiomers of rac-6-methylpyridine-2-methanol (3) undergo a self-recognition process to form exclusively homochiral helicates in which the four pyridine-alc. units possess the same chirality. In the experiment, the researchers used many compounds, for example, 6-Methyl-2-pyridinemethanol (cas: 1122-71-0Electric Literature of C7H9NO).
6-Methyl-2-pyridinemethanol (cas: 1122-71-0) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Electric Literature of C7H9NO
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts